Participation of brainstem nuclei in the pronociceptive effect of lesion or neural block of the anterior pretectal nucleus in a rat model of incisional pain

CF Villarreal, VAV Kina, WA Prado - Neuropharmacology, 2004 - Elsevier
The anterior pretectal nucleus (APtN) participates in nociceptive process and controls spinal
nociceptive inputs, and its integrity reduces the severity of the responses to persistent injury …

Descending mechanisms activated by the anterior pretectal nucleus initiate but do not maintain neuropathic pain in rats

AC Rossaneis, K Genaro, QM Dias… - … Journal of Pain, 2015 - Wiley Online Library
Background The anterior pretectal nucleus (APtN) activates descending mechanisms of pain
control. This study evaluated whether the APtN also controls neuropathic pain in rats …

Involvement of the anterior pretectal nucleus in the control of persistent pain: a behavioral and c-Fos expression study in the rat

CF Villarreal, EA Del Bel, AW Prado - Pain, 2003 - journals.lww.com
The anterior pretectal nucleus (APtN) participates in nociceptive processing and in the
activation of central descending mechanisms of pain control. In this study we used …

Modulation of persistent nociceptive inputs in the anterior pretectal nucleus of the rat

CF Villarreal, WA Prado - Pain, 2007 - Elsevier
The anterior pretectal nucleus (APtN) participates in nociceptive and antinociceptive
mechanisms. Drugs were injected into the ventral APtN to evaluate how intrinsic …

The ventral portion of the anterior pretectal nucleus controls descending mechanisms that initiate neuropathic pain in rats

AC Rossaneis, WA Prado - Clinical and Experimental …, 2015 - Wiley Online Library
Stimulating the dorsal anterior pretectal nucleus (dAPtN) in rats is more effective than
stimulating the ventral AP tN (vAPtN) at reducing tail‐flick latency, whereas stimulation of the …

[HTML][HTML] The antinociceptive effect of anterior pretectal nucleus stimulation is mediated by distinct neurotransmitter mechanisms in descending pain pathways

K Genaro, D Fabris, WA Prado - Brain Research Bulletin, 2019 - Elsevier
Electrical stimulation of the anterior pretectal nucleus (APtN) activates two descending pain
inhibitory pathways. One of these pathways relays in the ipsilateral lateral …

Antinociception induced by stimulating the anterior pretectal nucleus in two models of pain in rats

CF Villarreal, VAV Kina… - Clinical and experimental …, 2004 - Wiley Online Library
This study examined whether different parts of the rat anterior pretectal nucleus (APtN) may
be involved in the spinal control of brief (tail flick test) or persistent (surgical incision of the …

The pontine parabrachial region mediates some of the descending inhibitory effects of stimulating the anterior pretectal nucleus

MG Terenzi, H Rees, MHT Roberts - Brain research, 1992 - Elsevier
Electrical stimulation of the anterior pretectal nucleus (APtN) elicits antinociception by
inhibiting the responses of spinal multireceptive neurones to noxious stimuli. This …

Pharmacological and neuroanatomical evidence for the involvement of the anterior pretectal nucleus in the antinociception induced by stimulation of the dorsal raphe …

MLNM Rosa, MA Oliveira, RB Valente, NC Coimbra… - Pain, 1998 - Elsevier
Several studies have shown that the anterior pretectal nucleus (APtN) is involved in
descending inhibitory pathways that control noxious inputs to the spinal cord and that it may …

[HTML][HTML] Neural correlates of the antinociceptive effects of stimulating the anterior pretectal nucleus in rats

K Genaro, WA Prado - The Journal of Pain, 2016 - Elsevier
Stimulation-evoked antinociception (SEA) from the anterior pretectal nucleus (APtN)
activates mechanisms that descend to the spinal cord through the dorsolateral funiculus, but …