Sexual assault samples are among the most difficult sample types encountered by forensic
laboratories. Typically, a sexual assault sample has multiple challenges including small …

We developed and validated the Investigator Quantiplex Pro Kit which quantifies human and
male DNA in a sample using quantitative real-time PCR. An internal PCR control (IPC) is …

Challenging samples were processed using alternative quantification and STR PCR
methods that include internal performance controls. These internal controls can be used to …

Accurate quantification of DNA samples is an important step in obtaining accurate and
reproducible short tandem repeat (STR) profiles. Quantitative real‐time‐PCR has improved …

At present, the forensic DNA workflow is not capable of providing information about the
contributor status (single source vs. mixtures) of evidentiary samples prior to end-point …

Accurate human-specific DNA quantification is essential for forensic casework analysis. In
this work, we describe a microplate-based quantification assay that utilizes the PCR …

In historical cases, ancient DNA investigations and missing persons identification, teeth or
bone samples are often the only and almost always the best biological material available for …

For optimal DNA short tandem repeat (STR) typing results, the DNA concentration ([DNA]) of
the sample must be accurately determined prior to the polymerase chain reaction (PCR) …

NIST Concordance Evaluations to Assist in the Improvement of Commercial STR Multiplex Kits
Page 1 Interpretation Errors Detected in a NIST Interlaboratory Study on DNA Mixture …

National Institute of Standards and Technology SRM 2372 human DNA quantitation
standard has been produced to support the need for a human-specific DNA quantitation …