A fundamental tenet of the laws of thennodynamics is that all systems proceed to maximum
entropy. To stay alive we must resist this force. After wounding, the systems of resistance are …

In the normal, healthy lung, elastin production is restricted to periods of development and
growth. However, elastin expression in the adult lung has been observed in some forms of …

Cultured lung fibroblasts produced and secreted interstitial collagen types I and III. The
relative proportion of type III collagen increased as a linear function of cell density, with …

Elastic and collagen fibers confer recoil and tensile strength on the pulmonary vasculature,
airways, alveolar walls, and pleura. These durable extracellular matrix components are …

The lung and other organs are comprised of both cellular and extracellular compartments.
Interaction of these components modulates physiological function at the organ, cellular, and …

The relationship between elastin degradation and emphysema is well known. Recent
evidence suggests that a complex process of pulmonary remodeling occurs within the …

Collagens of various types are the major group of proteins in the lung. They are present in
all major structures, including airways, blood vessels, the interstitium of the lung …

Elastic fibers are important for elasticity and extensibility of lung tissue. In the developing
lung, elastic fibers appear in greatest numbers during the process or period of …

Irreversible abnormalities of lung architecture are hallmarks of many acute and chronic
diseases. Lung cavities in gram-negative bacterial pneumonias and pulmonary tuberculosis …