Elastin expression in very severe human COPD

G Deslee, JC Woods, CM Moore, L Liu… - European respiratory …, 2009 - Eur Respiratory Soc
Alveolar elastic fibres are key targets of proteases during the pathogenesis of chronic
obstructive pulmonary disease (COPD). In the current study, we hypothesised that a …

Matrix proteoglycans in development of pulmonary edema

D Negrini, A Passi, G de Luca… - Proteoglycans in lung …, 2002 - taylorfrancis.com
Matrix Proteoglycans in Development of Pulmonary Edema Page 1 8 Matrix Proteoglycans in
Development of Pulmonary Edema DANIELA NEGRINI, ALBERTO GIUSEPPE MISEROCCHI …

Proteoglycan changes in the extracellular matrix of lung tissue from patients with pulmonary emphysema.

JF Van Straaten, W Coers, JA Noordhoek… - Modern pathology: an …, 1999 - europepmc.org
To characterize the changes in the extracellular matrix in smoking-related pulmonary
emphysema, we undertook immunohistochemical studies in lung tissues from controls (n …

Bronchoalveolar lavage desmosine in bleomycin-induced lung injury in marmosets and patients with adult respiratory distress syndrome

S Idell, RS Thrall, R Maunder, TR Martin… - Experimental Lung …, 1989 - Taylor & Francis
Measurement of urinary desmosine in experimental models of emphysema has been used
to demonstrate elastin catabolism. In order to evaluate the hypothesis that accelerated …

Roles of mechanical forces and collagen failure in the development of elastase-induced emphysema

S Kononov, K Brewer, H Sakai… - American journal of …, 2001 - atsjournals.org
Emphysema causes a permanent destruction of alveolar walls leading to airspace
enlargement, loss of elastic recoil, decrease in surface area for gas exchange, lung …

Elastin turnover in murine lung after repeated ozone exposure

MA Dubick, RB Rucker, JA Last, LO Lollini… - Toxicology and Applied …, 1981 - Elsevier
Several lines of evidence suggest that ozone (O3) may affect the connective tissue elements
of the lung. Since alterations in the elastic properties of lung parenchyma have been …

Elastin content of normal and emphysematous lung parenchyma

P Chrzanowski, S Keller, J Cerreta, I Mandl… - The American journal of …, 1980 - Elsevier
Elastin destruction has been recognized as a crucial factor in the development of
experimental pulmonary emphysema. However, no consistent alterations in lung elastin …

Repair of chronic hyperoxic lung injury: changes in lung ultrastructure and matrix

RA Durr, BA Dubaybo, LA Thet - Experimental and molecular pathology, 1987 - Elsevier
We studied changes in lung ultrastructure, fibronectin, and collagen during repair of chronic
hyperoxic lung injury induced by exposure of rats to 85% oxygen for 14 days …

Pulmonary fibroelastosis-a review

DJK Yombo, S Madala, CP Vemulapalli, HH Ediga… - Matrix Biology, 2023 - Elsevier
Elastin is a long-lived fibrous protein that is abundant in the extracellular matrix of the lung.
Elastic fibers provide the lung the characteristic elasticity during inhalation with recoil during …

Proteoglycan deposition in pulmonary fibrosis.

ES Bensadoun, AK Burke, JC Hogg… - American journal of …, 1996 - atsjournals.org
This study compares the deposition of proteoglycans in the extracellular matrix of the lung
lesions of the adult respiratory distress syndrome (ARDS) and bronchiolitis obliterans …