Red blood cell transfusion and transfusion alternatives in traumatic brain injury

AH Kramer, P Le Roux - Current treatment options in neurology, 2012 - Springer
Opinion statement Anemia develops in about 50% of patients hospitalized with traumatic
brain injury (TBI) and is recognized as a cause of secondary brain injury. This review …

The effects of anaemia and transfusion on patients with traumatic brain injury: a review

S Travers, S Martin, NS Litofsky - Brain Injury, 2016 - Taylor & Francis
Background: Anaemia in traumatic brain injury (TBI) is frequently encountered.
Neurosurgical texts continue to recommend transfusion for hematocrit below 30%, despite …

Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol

A Boutin, M Chassé, M Shemilt, F Lauzier, L Moore… - Systematic reviews, 2014 - Springer
Background Anemia is a prevalent condition in critically ill patients and red blood cell
transfusions are frequent. Although transfusions at low hemoglobin levels have been shown …

Transfusion practices in traumatic brain injury

JM East, J Viau-Lapointe… - Current Opinion in …, 2018 - journals.lww.com
Currently, there is insufficient evidence to make strong recommendations regarding which
hemoglobin threshold to use as a transfusion trigger in critically-ill patients with TBI. There is …

Anemia in the setting of traumatic brain injury: the arguments for and against liberal transfusion

GH Utter, K Shahlaie, M Zwienenberg-Lee… - Journal of …, 2011 - liebertpub.com
Anemia is recognized as a possible cause of secondary injury following traumatic brain
injury (TBI). Cogent arguments can be made for both liberal and restrictive blood transfusion …

TRansfusion strategies in Acute brain INjured patients (TRAIN): a prospective multicenter randomized interventional trial protocol

FS Taccone, R Badenes, CB Rynkowski, P Bouzat… - Trials, 2023 - Springer
Background Although blood transfusions can be lifesaving in severe hemorrhage, they can
also have potential complications. As anemia has also been associated with poor outcomes …

Red blood cell transfusion in patients with traumatic brain injury: a systematic review and meta-analysis

A Boutin, M Chassé, M Shemilt, F Lauzier… - Transfusion medicine …, 2016 - Elsevier
Our objectives were to evaluate the frequency of red blood cell (RBC) transfusion in patients
with traumatic brain injury (TBI) as well as potential determinants and outcomes associated …

Retrospective evaluation of anemia and transfusion in traumatic brain injury

AP Carlson, CR Schermer, SW Lu - Journal of Trauma and Acute …, 2006 - journals.lww.com
Background: Despite clear evidence in critical care that blood transfusion has an adverse
impact on outcome, neurosurgical textbooks still recommend transfusion of patients with …

Transfusion strategies in patients with traumatic brain injury: which is the optimal hemoglobin target?

C Lelubre, FS Taccone - Minerva anestesiologica, 2015 - europepmc.org
Robertson et al.(JAMA 2014; 312: 36-47) investigated the effects of two different thresholds
of hemoglobin (Hb) to guide red blood cells transfusions (RBCT; 7 g/dL vs. 10 g/dL) in …

Anemia management after acute brain injury

C Lelubre, P Bouzat, IA Crippa, FS Taccone - Critical care, 2016 - Springer
Anemia is frequent among brain-injured patients, where it has been associated with an
increased risk of poor outcome. The pathophysiology of anemia in this patient population …