Skin toxicities associated with epidermal growth factor receptor inhibitors
T Li, R Perez-Soler - Targeted oncology, 2009 - Springer
The use of epidermal growth factor receptor (EGFR) inhibitors in several epithelial tumors
has increased considerably in recent years. Currently, they are approved in non-small cell …
has increased considerably in recent years. Currently, they are approved in non-small cell …
Cutaneous side effects of epidermal growth factor receptor inhibitors: clinical presentation, pathogenesis, and management
JC Hu, P Sadeghi, LC Pinter-Brown, S Yashar… - Journal of the American …, 2007 - Elsevier
The growing investigation and use of epidermal growth factor receptor (EGFR) inhibitors in
anticancer therapy has been motivated by their specificity for EGFR, which improves their …
anticancer therapy has been motivated by their specificity for EGFR, which improves their …
Impact and management of skin toxicity associated with anti-epidermal growth factor receptor therapy: survey results
SL Boone, A Rademaker, D Liu, C Pfeiffer, DJ Mauro… - Oncology, 2008 - karger.com
Biologic agents targeting the epidermal growth factor receptor (EGFR) have emerged as a
robust treatment option for various solid tumors. Despite lower systemic side effects than …
robust treatment option for various solid tumors. Despite lower systemic side effects than …
[HTML][HTML] Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors
S Segaert, E Van Cutsem - Annals of oncology, 2005 - Elsevier
The last few years, new therapies targeting the epidermal growth factor receptor (EGFR)
have shown their efficacy in the treatment of several types of cancer. Monoclonal antibodies …
have shown their efficacy in the treatment of several types of cancer. Monoclonal antibodies …
Epidermal growth factor receptor inhibitor–related skin toxicity: mechanisms, treatment, and its potential role as a predictive marker
D Bianchini, A Jayanth, YJ Chua… - Clinical colorectal cancer, 2008 - Elsevier
The human epidermal growth factor receptor (HER1/EGFR/ErbB1) signaling is aberrant and
overexpressed in many solid malignancies making it an appealing target for biologic agents …
overexpressed in many solid malignancies making it an appealing target for biologic agents …
Epidermal growth factor receptor inhibitor–associated cutaneous toxicities: an evolving paradigm in clinical management
TJ Lynch Jr, ES Kim, B Eaby, J Garey, DP West… - The …, 2007 - academic.oup.com
Epidermal growth factor receptor inhibitors (EGFRIs) have demonstrated improved overall
survival in patients with non-small cell lung cancer, pancreatic cancer, and colorectal …
survival in patients with non-small cell lung cancer, pancreatic cancer, and colorectal …
Mechanisms underlying skin disorders induced by EGFR inhibitors
M Holcmann, M Sibilia - Molecular & cellular oncology, 2015 - Taylor & Francis
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is frequently
mutated or overexpressed in a large number of tumors such as carcinomas or glioblastoma …
mutated or overexpressed in a large number of tumors such as carcinomas or glioblastoma …
Dermatologic side effects associated with the epidermal growth factor receptor inhibitors
ALC Agero, SW Dusza, C Benvenuto-Andrade… - Journal of the American …, 2006 - Elsevier
Epidermal growth factor receptor (EGFR) inhibitors are associated with unique and dramatic
dermatologic side effects. Cetuximab, erlotinib, and gefitinib have been approved for …
dermatologic side effects. Cetuximab, erlotinib, and gefitinib have been approved for …
Recommendations for the prophylactic management of skin reactions induced by epidermal growth factor receptor inhibitors in patients with solid tumors
RD Hofheinz, G Deplanque, Y Komatsu… - The …, 2016 - academic.oup.com
Inhibition of the epidermal growth factor receptor (EGFR) is an established treatment that
extends patient survival across a variety of tumor types. EGFR inhibitors fall into two main …
extends patient survival across a variety of tumor types. EGFR inhibitors fall into two main …
Safety and tolerability of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in oncology
RR Shah, DR Shah - Drug safety, 2019 - Springer
Tyrosine kinase inhibitors (TKIs) that target epidermal growth factor receptor (EGFR) have
dramatically improved progression-free survival in non-small-cell lung cancer (NSCLC) …
dramatically improved progression-free survival in non-small-cell lung cancer (NSCLC) …
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