The purine analog xanthine oxidase (XO) inhibitors (XOIs), allopurinol and oxypurinol, have
been reported to protect against heart failure secondary to myocardial infarction or rapid …

It has been widely proposed that conversion of xanthine dehydrogenase (XDH) to its free
radical-producing form, xanthine oxidase (XOD), underlies ischemic/reperfusion injury …

Age-dependent differences in the effects of ischemia and reperfusion on ATP breakdown
were studied in perfused adult and newborn (10 days old) rat hearts. No-flow ischemia (15 …

Xanthine oxidoreductase (XOR) is increased in the left ventricle (LV) of humans with volume
overload (VO), and mitochondrial inhibition of the respiratory chain occurs in animal models …

Xanthine oxidoreductase (XOR) can exist in a dehydrogenase form (XD) and an oxidase
form (XO). The D-form uses NAD as cofactor and the O-form uses oxygen as second …

The enzyme xanthine oxidoreductase (XOR) is an important source of oxygen free radicals
and related postischemic injury. Xanthine dehydrogenase (XDH), the major form of XOR in …

Xanthine oxidase (EC 1.1. 3.22) and xanthine dehydrogenase (EC 1.1. 1.204) are both
members of the molybdenum hydroxylase flavoprotein family and represent different forms …

The generation of a monoclonal antibody specific to xanthine oxidase and its use in the
distribution of the enzyme in human tissue is described. Xanthine oxidase was purified from …

Endothelial xanthine oxidoreductase (XOR) together with NAD (P) H oxidase and nitric
oxide (NO) synthase plays a physiologic role in inflammatory signalling, the regulation of NO …

High-energy phosphates in heart muscle deprived of oxygen are rapidly broken down to
purine nucleosides and oxypurines. We studied the role of xanthine oxidase/dehydrogenase …