Consumption of goats' milk protects mice from carbon tetrachloride-induced acute hepatic injury and improves the associated gut microbiota imbalance

J Zhang, Z Wang, D Huo, Y Shao - Frontiers in Immunology, 2018 - frontiersin.org
Drugs used to treat liver diseases have serious side effects; it is important to search for safe
functional foods with hepatoprotective functions and few side effects. In this study, potential …

Vine Tea (Ampelopsis grossedentata) Extract Attenuates CCl4‐Induced Liver Injury by Restoring Gut Microbiota Dysbiosis in Mice

Y Li, H Hu, H Yang, A Lin, H Xia… - Molecular Nutrition & …, 2022 - Wiley Online Library
Scope Vine tea (Ampelopsis grossedentata), a traditional Chinese tea, has displayed
various biological activities. The authors aim to investigate the effect of Vine Tea …

The hepatoprotective effect of the probiotic Clostridium butyricum against carbon tetrachloride-induced acute liver damage in mice

J Liu, Y Fu, H Zhang, J Wang, J Zhu, Y Wang, Y Guo… - Food & function, 2017 - pubs.rsc.org
Previous studies have revealed that the probiotic Clostridium butyricum (C. butyricum) can
attenuate cirrhosis in chronic non-alcoholic liver disease. However, the effects of C …

Western Diet Aggravated Carbon Tetrachloride‐Induced Chronic Liver Injury by Disturbing Gut Microbiota and Bile Acid Metabolism

L Yang, Y Li, S Wang, X Bian, X Jiang… - Molecular Nutrition & …, 2021 - Wiley Online Library
Scope The high‐fat, high‐sucrose, and low‐fiber Western diet (WD) is popular in many
countries and affects the onset and progression of many diseases. This study is aimed to …

Protective Effect of Lactiplantibacillus plantarum 1201 Combined with Galactooligosaccharide on Carbon Tetrachloride-Induced Acute Liver Injury in Mice

Z Ren, Y Huo, Q Zhang, S Chen, H Lv, L Peng, H Wei… - Nutrients, 2021 - mdpi.com
Acute liver injury (ALI) has a high mortality rate of approximately 20–40%, and it is
imperative to find complementary and alternative drugs for treating ALI. A carbon …

A study to evaluate the hepatoprotective activity of prebiotics, probiotics, and synbiotic in CCl4 induced hepatotoxicity in rats

AB Devi, AB Rahigude, PB Parab… - Journal of Applied …, 2021 - japsonline.com
The current study was evaluated for the hepatoprotective activity of probiotics, prebiotics
alone, and synbiotic of them. Animals were grouped into 12 groups (n= 6), ie normal control …

Ameliorative effects of chlorogenic acid on alcoholic liver injury in mice via gut microbiota informatics

H Zhu, W Jiang, C Liu, C Wang, B Hu, Y Guo… - European Journal of …, 2022 - Elsevier
Chlorogenic acid (CGA) is a functional phenolic acid widely used in food and medicine-
related fields. It has been proved to be effective in the treatment of alcoholic liver disease …

Scutellarein Aggravated Carbon Tetrachloride‐Induced Chronic Liver Injury in Gut Microbiota‐Dysbiosis Mice

Z Miao, Y Lai, Y Zhao, L Chen, J Zhou… - Evidence‐Based …, 2020 - Wiley Online Library
Scutellarein (SCU) is an herbal flavonoid, showing hepatoprotective potentials. The study
was aimed to investigate whether the hepatoprotective effect of SCU is dependent on the …

Combining fecal microbiome and metabolomics to reveal the disturbance of gut microbiota in liver injury and the therapeutic mechanism of shaoyao gancao decoction

J Li, M Zhao, J Li, M Wang, C Zhao - Frontiers in Pharmacology, 2022 - frontiersin.org
Chemical liver injury is closely related to gut microbiota and its metabolites. In this study, we
combined 16S rRNA gene sequencing, 1H NMR-based fecal metabolomics and GC-MS to …

Gut microbiota and chemical-induced acute liver injury

T Chen, R Li, P Chen - Frontiers in physiology, 2021 - frontiersin.org
Background: Drug overdose or chemical exposures are the main causes of acute liver injury
(ALI). Severe liver injury can develop into liver failure that is an important cause of liver …