In the early phase of their disease process, patients with acute lung injury are often
ventilated with strategies that control the tidal volume or airway pressure, while modes …

We update and summarize the role of spontaneous breathing during mechanical ventilation
in ARDS, which can be beneficial or deleterious, depending on the strength of spontaneous …

Objective: We investigated whether potentially injurious transpulmonary pressure could be
generated by strong spontaneous breathing and exacerbate lung injury even when plateau …

Intensive Care Med (1999) 25: 1203±1205© Springer-Verlag 1999 EDITORIAL the
diaphragm, most evident in the posterior lung units during mechanical ventilation [11]. It has …

In our opinion, spontaneous breathing activity should be avoided in the first 48 h of
mechanical ventilation in patients with severe ARDS (PaO 2/FIO 2< 120 mmHg), but it may …

Improved gas exchange has been observed during spontaneous breathing with airway
pressure release ventilation (APRV) as compared with controlled mechanical ventilation …

Optimizing gas exchange, avoiding lung injury, and preserving respiratory muscle strength
and endurance are vital therapeutic objectives for managing acute lung injury. Accordingly …

Based on available data, it can be suggested that spontaneous breathing during ventilator
support has not to be suppressed even in patients with severe pulmonary dysfunction if no …

Airway pressure release ventilation (APRV) and bi-level positive airway pressure (BIPAP)
are proposed to reduce patient work of breathing (WOB) sufficiently and to obviate issues …

Introduction Inspiratory pressure support (IPS) is a new mode of assisted ventilation
designed to support spontaneously breathing patients (1-3). During inspiration, a …