Abstract Background and Objective The effect of renal impairment on colchicine
pharmacokinetics in patients with chronic kidney disease (CKD) has not been studied …

Aims Colchicine has an emerging role in the cardiovascular field, although, concerns for
side effects, especially gastrointestinal, limit its prescription. We aimed at evaluating …

The clinical pharmacology of colchicine has been reviewed and its therapeutic use
described. There is still some disagreement about its diagnostic utility; it is clearly most …

Colchicine is a tricyclic, lipid-soluble alkaloid derived from the plant of the Lily family
Colchicum autumnale, sometimes called the “autumn crocus”. It is predominantly …

Purified from a Mediterranean plant nearly two centuries ago, colchicine has been
discovered to inhibit many steps in the inflammatory process. The drug has good oral …

Colchicine is an old anti-inflammatory drug that has shown substantial cardiovascular
benefits in recent trials. We systematically reviewed cardiovascular benefits and harms of …

For many years, colchicine has been used for therapeutic purposes and has been given
considerable attention because of its association with tubulin and inhibition of small tubular …

Inflammation plays a prominent role in the development of atherosclerosis and other
cardiovascular diseases, and anti-inflammatory agents may improve cardiovascular …

Introduction. Colchicine is used mainly for the treatment and prevention of gout and for
familial Mediterranean fever (FMF). It has a narrow therapeutic index, with no clear-cut …

Background Colchicine is a widely used drug to treat inflammatory diseases. Due to its long
historical use in medicine, controlled clinical trials have been small and there remains some …