Background Experimental and clinical evidence supports the role of inflammation in
atherosclerosis and its complications. Colchicine is an orally administered, potent …

The pharmacokinetics of colchicine were studied in six healthy male and four elderly female
volunteers after iv and oral administration. Plasma samples were collected over 72 h and …

OBJECTIVE To report a case of colchicine intoxication occurring with institution of
clarithromycin. CASE SUMMARY A 76-year-old man with familial Mediterranean fever (FMF) …

Published experiences with severe toxicity with intravenous colchicine have been reviewed.
All reported cases reflect inappropriate use of the drug. Therapeutic rules for colchicine have …

Two of our patients experienced myotoxicity associated with colchicine administration. The
first was a 54‐year‐old woman who was receiving dialysis and came to the emergency …

1 A specific and sensitive radioimmunoassay was used to study the toxicokinetics of
colchicine in seven cases of acute human poisoning. Post-mortem tissue concentrations of …

Colistin, the most widely used polymyxin antibiotic, was originally introduced in the late
1950s before the establishment of the present‐day drug approval process. Originally …

In order to establish the degree of renal malfunction necessary for colchicine toxicity in
patients receiving it daily for the prevention of recurrent acute gout, we obtained serum …