The role of hydrogen sulfide in normal and aberrant late lung development

A Madurga Hernández - 2015 - jlupub.ub.uni-giessen.de
Bronchopulmonary dysplasia (BPD) is a chronic lung disease characterized by arrested
alveolarization, a complication of premature birth. The gasotransmitter hydrogen sulfide …

Systemic hydrogen sulfide administration partially restores normal alveolarization in an experimental animal model of bronchopulmonary dysplasia

A Madurga, I Mižíková, J Ruiz-Camp… - … of Physiology-Lung …, 2014 - journals.physiology.org
Arrested alveolarization is the pathological hallmark of bronchopulmonary dysplasia (BPD),
a complication of premature birth. Here, the impact of systemic application of hydrogen …

[HTML][HTML] Exogenous Hydrogen Sulfide (H2S) Protects Alveolar Growth in Experimental O2-Induced Neonatal Lung Injury

A Vadivel, RS Alphonse, L Ionescu, DS Machado… - PLoS …, 2014 - journals.plos.org
Background Bronchopulmonary dysplasia (BPD), the chronic lung disease of prematurity,
remains a major health problem. BPD is characterized by impaired alveolar development …

Hydrogen Sulfide and Airway Hyperreactivity in a Mouse Model of Neonatal Hyperoxia Exposure

M Schiliro, B Roos, LL Nesbitt, SA Wicher… - … OF LUNG GROWTH …, 2021 - atsjournals.org
Rationale: Supplemental oxygen is often required following preterm birth but is unfortunately
associated with development of chronic lung disease and airway hyperreactivity (AHR) …

Understanding hydrogen sulfide signaling in neonatal airway disease

M Schiliro, CM Bartman, C Pabelick - Expert review of respiratory …, 2021 - Taylor & Francis
Introduction Airway dysfunction leading to chronic lung disease is a common consequence
of premature birth and mechanisms responsible for early and progressive airway …

The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization

A Madurga, A Golec, A Pozarska… - … of Physiology-Lung …, 2015 - journals.physiology.org
The gasotransmitter hydrogen sulfide (H2S) is emerging as a mediator of lung physiology
and disease. Recent studies revealed that H2S administration limited perturbations to lung …

Exogenous hydrogen sulfide attenuates hyperoxia effects on neonatal mouse airways

CM Bartman, M Schiliro, L Nesbitt… - … of Physiology-Lung …, 2024 - journals.physiology.org
Supplemental O2 remains a necessary intervention for many premature infants (< 34 wk
gestation). Even moderate hyperoxia (< 60% O2) poses a risk for subsequent airway …

[HTML][HTML] Hydrogen Sulfide—Clues from Evolution and Implication for Neonatal Respiratory Diseases

A Ganguly, G Ofman, PF Vitiello - Children, 2021 - mdpi.com
Reactive oxygen species (ROS) have been the focus of redox research in the realm of
oxidative neonatal respiratory diseases such as bronchopulmonary dysplasia (BPD). Over …

Hydrogen Sulfide (H2S), Mitochondria and Oxygen in Developing Airway Smooth Muscle

M Schiliro, CM Bartman, KE Stelzig… - … OF LUNG GROWTH …, 2021 - atsjournals.org
Rationale. Premature birth and a consequent immature respiratory system necessitate use
of supplemental oxygen in the immediate postnatal period. It is now recognized that even …

Hydrogen sulfide: a novel player in airway development, pathophysiology of respiratory diseases, and antiviral defenses

N Bazhanov, M Ansar, T Ivanciuc… - American journal of …, 2017 - atsjournals.org
Hydrogen sulfide (H2S) is a biologically relevant signaling molecule in mammals. Along with
the volatile substances nitric oxide (NO) and carbon monoxide (CO), H2S is defined as a …