Inhibition of tumour growth in vitro by bromelain, an extract of the pineapple plant (Ananas comosus)

SJ Taussig, J Szekerczes, S Batkin - Planta medica, 1985 - thieme-connect.com
Non steroidal anti-inflammatory drugs such as aspirin and indomethacin associated with
inhibition of platelet aggregation (1, 2, 3) have been reported to retard tumour growth (4) …

Antimetastatic effect of bromelain with or without its proteolytic and anticoagulant activity

S Batkin, SJ Taussig, J Szekerezes - Journal of cancer research and …, 1988 - Springer
Bromelain, a pineapple-derived plant product, added to C57B1/6 mice laboratory chow
decreased lung metastasis of Lewis lung cancer cells implanted sc This antimetastatic …

On the pharmacology of bromelain: an update with special regard to animal studies on dose-dependent effects

H Lotz-Winter - Planta medica, 1990 - thieme-connect.com
Bromelain, a standardized complex of proteases from the pineapple plant, is absorbed
unchanged from the intestine of animals at a rate of 40%; in animal experiments it was found …

Bromelain, the enzyme complex of pineapple (Ananas comosus) and its clinical application. An update

SJ Taussig, S Batkin - Journal of ethnopharmacology, 1988 - Elsevier
After a short description of the uses of pineapple as folk medicine by the natives of the
troplcs, the more important new pharmaceutical applications of bromelain, reported between …

Modulation of pulmonary metastasis (Lewis lung carcinoma) by bromelain, an extract of the pineapple stem (Ananas comosus)

S Batkin, S Taussig, J Szekerczes - Cancer Investigation, 1988 - Taylor & Francis
Our recent studies, in vitro, with bromelain, a natural product, indicated specific retardation of
Lewis lung carcinoma, YC-8 lymphoma, and MCA-1 ascitic tumor cells (1) as well as a …

Antimetastatic effect of flurbiprofen and other platelet aggregation inhibitors.

A Mamytbekova, K Rezabek, H Kacerovska… - Neoplasma, 1986 - europepmc.org
In the present study, we have examined the antimetastatic effect of flurbiprofen, a
nonsteroidal antiinflammatory drug, on spontaneous metastases formation in mice bearing …

Forskolin: a potential antimetastatic agent

KC Agarwal, RE Parks Jr - International journal of cancer, 1983 - Wiley Online Library
Forskolin, a diterpene from the roots of an Indian plant, Coleus forskohlii, is a potent platelet
aggregation inhibitor and has been examined for its effects on (a) tumor‐induced human …

Possible involvement of eicosanoids in the pharmacological action of bromelain.

M Vellini, D Desideri, A Milanese, C Omini… - Arzneimittel …, 1986 - europepmc.org
Bromelain, a proteolytic enzyme extracted from pineapple plants, was investigated for its
capacity to interfere with arachidonic acid metabolism, since prostaglandins and other …

Effects of onion (Allium cepa) extract on platelet aggregation and thromboxane synthesis

AN Makheja, JY Vanderhoek, JM Bailey - Prostaglandins and medicine, 1979 - Elsevier
Oral administration of onion and garlic reportedly decreases platelet aggregation in both
human and animal subjects. An oily chloroform extract of onion (Allium Cepa) was prepared …

Potential inhibitors of platelet aggregation from plant sources, III

HS Yun-Choi, JH Kim, JR Lee - Journal of natural products, 1987 - ACS Publications
ABSTRACT.—3, 4-Dihydroxy benzoic acid (DBA) was isolated from Acanthopanax
senticosus as an antiplatelet aggregatory substance. This paperalso reports the results of …