Synthesis and α-Glucosidase Inhibition Activity of 2-[3-(Benzoyl/4-bromobenzoyl)-4-hydroxy-1,1-dioxido-2H-benzo[e][1,2]thiazin-2-yl]-N-arylacetamides: An In Silico …
Diabetes mellitus (DM) is a chronic disorder and has affected a large number of people
worldwide. Insufficient insulin production causes an increase in blood glucose level that …
worldwide. Insufficient insulin production causes an increase in blood glucose level that …
Novel indolyl linked para-substituted benzylidene-based phenyl containing thiazolidienediones and their analogs as α-glucosidase inhibitors: synthesis, in vitro, and …
Synthesis of indolyl linked benzylidene-based para-substituted phenyl containing
thiazolidinediones and acyclic analogs of isoxazolidinediones—a cyclic analog of …
thiazolidinediones and acyclic analogs of isoxazolidinediones—a cyclic analog of …
Synthesis, molecular modeling and biological evaluation of 5-arylidene-N, N-diethylthiobarbiturates as potential α-glucosidase inhibitors
Background: Barbituric acid derivatives are a versatile group of compounds which are
identified as potential pharmacophores for the treatment of anxiety, epilepsy and other …
identified as potential pharmacophores for the treatment of anxiety, epilepsy and other …
Synthesis, α‐glucosidase Inhibition, in silico Pharmacokinetic, and Docking Studies Of Thieno[2,3‐b]Quinoline‐Acetamide Derivatives as New Anti‐Diabetic Agents
M Mohammadi‐Khanaposhtani, M Noori… - …, 2022 - Wiley Online Library
In this work, novel anti‐α‐glucosidase agents, thieno [2, 3‐b] quinoline‐acetamide
derivatives 5 a–m have been designed and synthesized. These compounds were evaluated …
derivatives 5 a–m have been designed and synthesized. These compounds were evaluated …
Novel Bis-Schiff's base derivatives of 4-nitroacetophenone as potent α-glucosidase agents: Design, synthesis and in silico approach
Bis-Schiff's base derivatives of 4-nitroacetophenone (1–18) were synthesized in good yields
by reacting hydrazone of 4-nitroacetophenone with substituted aldehydes and ketones with …
by reacting hydrazone of 4-nitroacetophenone with substituted aldehydes and ketones with …
Synthesis of Novel 2,3-Dihydro-1,5-Benzothiazepines as α-Glucosidase Inhibitors: In Vitro, In Vivo, Kinetic, SAR, Molecular Docking, and QSAR Studies
R Mehmood, EU Mughal, EB Elkaeed, RJ Obaid… - ACS …, 2022 - ACS Publications
In the present study, a series of 2, 3-dihydro-1, 5-benzothiazepine derivatives 1B–14B has
been synthesized sand characterized by various spectroscopic techniques. The enzyme …
been synthesized sand characterized by various spectroscopic techniques. The enzyme …
Synthesis, in vitro and computational studies of novel glycosyl-1, 2, 3-1H-triazolyl methyl benzamide derivatives as potential α-glucosidase inhibitory activity
AK Shukla, MK Shrivash, A Pandey, J Pandey - Bioorganic Chemistry, 2021 - Elsevier
A series of novel glycosyl-1, 2, 3-1H-triazolyl methyl benzamide analogues were
synthesized by the unambiguous strategy and evaluated for α-glucosidase inhibitory activity …
synthesized by the unambiguous strategy and evaluated for α-glucosidase inhibitory activity …
Synthesis, in vitro α-glucosidase inhibitory activity and molecular docking studies of new thiazole derivatives
Current study based on the synthesis of new thiazole derivatives via “one pot”
multicomponent reaction, evaluation of their in vitro α-glucosidase inhibitory activities, and in …
multicomponent reaction, evaluation of their in vitro α-glucosidase inhibitory activities, and in …
Synthesis and structure–activity relationship studies of benzimidazole-thioquinoline derivatives as α-glucosidase inhibitors
S Moghadam Farid, M Noori, M Nazari Montazer… - Scientific Reports, 2023 - nature.com
In this article, different s-substituted benzimidazole-thioquinoline derivatives were designed,
synthesized, and evaluated for their possible α-glucosidase inhibitory activities. The most …
synthesized, and evaluated for their possible α-glucosidase inhibitory activities. The most …
Novel coumarin containing dithiocarbamate derivatives as potent α-glucosidase inhibitors for management of type 2 diabetes
M Mollazadeh… - Medicinal …, 2021 - ingentaconnect.com
Background: α-Glucosidase is a hydrolyzing enzyme that plays a crucial role in the
degradation of carbohydrates and starch to glucose. Hence, α-glucosidase is an important …
degradation of carbohydrates and starch to glucose. Hence, α-glucosidase is an important …