Although most long QT syndromes (LQTSs) are associated with ion channel gene mutations,
the phenotype of the disease cannot be completely explained by what happens in the heart …

The long QT syndromes (LQTS) were the first genetically defined arrhythmia-prone
phenotype, and they still have much to teach arrhythmia doctors. At one time, patients with …

Since it was first reported 50 years ago, the long QT syndrome (LQTS) is now recognized as
a genetic disease caused by mutations of ion channel genes encoding a cardiac channel …

The potassium and sodium ion channels defective in the long QT syndromes (LQTS) are
present in the atria as well as the ventricles, so atrial arrhythmias may be anticipated in …

The case of a 19-year-old girl who was treated since she was 11 years of age for what was
thought to be a seizure disorder is presented. Various anticonvulsants (carbamazepine …

Background Congenital long QT syndrome (LQTS) is a heritable cardiac disease whereby
patients are at an increased risk for LQTS-triggered syncope, seizures, and sudden cardiac …

In 1856, Meissner described the death of a “deafmute girl, who collapsed and died while
being publicly admonished” by her school director for a misdemeanor. The girl also had 2 …

For half a century, the relationship between the QT interval and cardiac arrhythmias has
been recognized, 1 although attention has focused primarily on prolongation of the QT. The …

Since the early description of its phenotypes, 1–3 congenital long QT syndrome (LQTS) has
been recognized as a disease entity showing prolonged QT intervals on electrocardiogram …

In their article in this issue of Circulation, Schwartz and colleagues 1 deliver not only an
important message in the rapidly advancing field of long QT syndrome but an equally …