The accompanying reports on chordoma are very welcomed and informative. This extremely
rare but behaviorally malignant tumor continues to lack biologic understanding, recognition …

OBJECTIVE This study aimed to provide data on extended outcomes in primary clival
chordomas, focusing on progression-free survival (PFS) and overall survival (OS) …

Background The purpose of this study was to discuss the optimal management of patients
with clival chordomas and provide an up‐to‐date review of the field. Methods A schematic …

Object Chordomas are rare malignant neoplasms arising predominantly at the sacrum and
skull base. They are uniformly lethal unless treated with aggressive resection and proton …

Background Treating chordoma through surgery alone is often ineffective. Thus, surgery
often performed with irradiation, with a reported 5-year survival rate of 60–75%. The clinical …

Introduction Chordoma is a malignant and aggressive tumor originating from remnants of the
primitive notochord and usually involving the axial skeleton. Spontaneous regression of …

Objective Clivus chordomas are semi-malignant, but infiltratively growing tumors. Currently,
a widely-accepted treatment concept encompasses maximal, but safe, surgical resection …

The management of clival chordoma remains problematic. We present the case of a 48-year-
old woman with clival chordoma who underwent multiple surgeries and radiation therapy …

Chordomas arise from the remnants of embryonic notochord and commonly present in the
skull base and sacrococcygeal regions. 1, 2 Surgery is the primary treatment for chordoma …

To the Editor: Chordoma is a very rare mesenchymal tumor with a low to intermediate
malignant grade. Due to its poor responsiveness to conventional chemotherapy or …