Rapid translocation of nanoparticles from the lung airspaces to the body
Nano-size particles show promise for pulmonary drug delivery, yet their behavior after
deposition in the lung remains poorly understood. In this study, a series of near-infrared …
deposition in the lung remains poorly understood. In this study, a series of near-infrared …
Nanoparticle formulations in pulmonary drug delivery
MM Bailey, CJ Berkland - Medicinal research reviews, 2009 - Wiley Online Library
The advent of nanotechnology has reignited interest in the lungs as a major route of drug
delivery for both systemic and local treatments. The large surface area of the lungs and the …
delivery for both systemic and local treatments. The large surface area of the lungs and the …
Toxicological hazards of inhaled nanoparticles—potential implications for drug delivery
PJA Borm, W Kreyling - Journal of nanoscience and …, 2004 - ingentaconnect.com
Nanoparticles (NP), here defined as particles with a diameter smaller then 100 nm, are
increasingly used in different applications, including drug carrier systems and to pass organ …
increasingly used in different applications, including drug carrier systems and to pass organ …
Inhaled drug delivery: Past, present, and future
Inhaled drug delivery has been an emerging route for the treatment of lung diseases with
clear advantages over oral and intravenous routes. However, the delivery efficacy is affected …
clear advantages over oral and intravenous routes. However, the delivery efficacy is affected …
The Lord of the Lungs: The essential role of pulmonary surfactant upon inhalation of nanoparticles
The rapid development of nanotechnology is opening a huge world of promising
possibilities in healthcare, but this is also increasing the necessity to study the potential risk …
possibilities in healthcare, but this is also increasing the necessity to study the potential risk …
Inhalable nanoparticles delivery targeting alveolar macrophages for the treatment of pulmonary tuberculosis
Pulmonary tuberculosis is a highly prevalent respiratory disease that affects approximately a
quarter of the world's population. The drug treatment protocol for tuberculosis is complex …
quarter of the world's population. The drug treatment protocol for tuberculosis is complex …
Nanocarriers as pulmonary drug delivery systems to treat and to diagnose respiratory and non respiratory diseases
M Smola, T Vandamme… - International journal of …, 2008 - Taylor & Francis
The purpose of this review is to discuss the impact of nanocarriers administered by
pulmonary route to treat and to diagnose respiratory and non respiratory diseases. Indeed …
pulmonary route to treat and to diagnose respiratory and non respiratory diseases. Indeed …
Patented therapeutic drug delivery strategies for targeting pulmonary diseases
Introduction: Pulmonary route is one of the preferred routes for the administration of
therapeutically active agents for systemic as well as localized delivery. Chronic obstructive …
therapeutically active agents for systemic as well as localized delivery. Chronic obstructive …
Physicochemical properties of nanoparticles regulate translocation across pulmonary surfactant monolayer and formation of lipoprotein corona
Interaction with the pulmonary surfactant film, being the first line of host defense, represents
the initial bio-nano interaction in the lungs. Such interaction determines the fate of the …
the initial bio-nano interaction in the lungs. Such interaction determines the fate of the …
Formulation and characterization of spray-dried powders containing nanoparticles for aerosol delivery to the lung
JOH Sham, Y Zhang, WH Finlay, WH Roa… - International journal of …, 2004 - Elsevier
Spray-drying is a common practice of powder preparation for a wide range of drugs. Spray-
dried powders can be used to deliver particles to the lungs via a dry powder inhaler (DPI) …
dried powders can be used to deliver particles to the lungs via a dry powder inhaler (DPI) …