Procalcitonin for individualizing antibiotic treatment: an update with a focus on COVID-19

S Wolfisberg, C Gregoriano… - Critical reviews in clinical …, 2022 - Taylor & Francis
Procalcitonin (PCT) is useful for differentiating between viral and bacterial infections and for
reducing the unnecessary use of antibiotics. As the rise of antimicrobial resistance reaches …

The use of procalcitonin as an antimicrobial stewardship tool and a predictor of disease severity in coronavirus disease 2019 (COVID-19)

GP Drewett, OC Smibert, NE Holmes… - Infection Control & …, 2022 - cambridge.org
To the Editor—Prior to the coronavirus disease 2019 (COVID-19) pandemic, serum
procalcitonin (PCT)-based antimicrobial stewardship (AMS) algorithms have been shown to …

Procalcitonin to guide antibacterial prescribing in patients hospitalised with COVID-19

S Hughes, N Mughal, LSP Moore - Antibiotics, 2021 - mdpi.com
Antibacterial prescribing in patients presenting with COVID-19 remains discordant to rates of
bacterial co-infection. Implementing diagnostic tests to exclude bacterial infection may aid …

Streamlining antibiotic therapy with procalcitonin protocols: consensus and controversies

S Haubitz, B Mueller, P Schuetz - Expert review of respiratory …, 2013 - Taylor & Francis
Accumulating evidence supports procalcitonin (PCT) as an accurate surrogate biomarker for
likelihood and severity of bacterial infections. In community-acquired pneumonia and other …

The role of procalcitonin results in antibiotic decision-making in coronavirus disease 2019 (COVID-19)

V Fabre, S Karaba, J Amoah, M Robinson… - Infection Control & …, 2022 - cambridge.org
Objective: To evaluate the role of procalcitonin (PCT) results in antibiotic decisions for
COVID-19 patients at hospital presentation. Design, setting, and participants: Multicenter …

Procalcitonin values fail to track the presence of secondary bacterial infections in COVID-19 ICU patients

E Harte, S Kumarasamysarma, B Phillips, O Mackay… - Antibiotics, 2023 - mdpi.com
The development of secondary bacterial infections in COVID-19 patients has been
associated with increased mortality and worse clinical outcomes. Consequently, many …

Procalcitonin and secondary bacterial infections in COVID-19: association with disease severity and outcomes

N Vazzana, F Dipaola, S Ognibene - Acta Clinica Belgica, 2022 - Taylor & Francis
Introduction Procalcitonin (PCT) is an emerging prognostic marker in coronavirus disease
2019 (COVID-19). Whether PCT can detect secondary bacterial infections or reflect target …

Evaluation of procalcitonin-guided antimicrobial stewardship in patients admitted to hospital with COVID-19 pneumonia

M Calderon, A Li, JC Bazo-Alvarez… - JAC-Antimicrobial …, 2021 - academic.oup.com
Background Procalcitonin is a biomarker that may be able to identify patients with COVID-19
pneumonia who do not require antimicrobials for bacterial respiratory tract co-infections …

Evaluation of procalcitonin as a contribution to antimicrobial stewardship in SARS-CoV-2 infection: a retrospective cohort study

EJ Williams, L Mair, TI de Silva, DJ Green… - Journal of Hospital …, 2021 - Elsevier
It can be a diagnostic challenge to identify patients with coronavirus disease 2019 in whom
antibiotics can be safely withheld. This study evaluated the effectiveness of a guideline …

Routine measurement of serum procalcitonin allows antibiotics to be safely withheld in patients admitted to hospital with SARS-CoV-2 infection

EJ Williams, L Mair, TI de Silva, DJ Green, P House… - medRxiv, 2020 - medrxiv.org
Background It can be a diagnostic challenge to identify COVID-19 patients without bacterial
co-infection in whom antibiotics can be safely stopped. We sought to evaluate the validity of …