Nuclear pore complexes guardians of the nuclear genome
M Capelson, C Doucet… - Cold Spring Harbor …, 2010 - symposium.cshlp.org
Eukaryotic cell function depends on the physical separation of nucleoplasmic and
cytoplasmic components by the nuclear envelope (NE). Molecular communication between …
cytoplasmic components by the nuclear envelope (NE). Molecular communication between …
Structure, maintenance, and regulation of nuclear pore complexes: the gatekeepers of the eukaryotic genome
M Raices, MA D'Angelo - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
In eukaryotic cells, the genetic material is segregated inside the nucleus. This
compartmentalization of the genome requires a transport system that allows cells to move …
compartmentalization of the genome requires a transport system that allows cells to move …
Functional interactions between nucleoporins and chromatin
Y Liang, MW Hetzer - Current opinion in cell biology, 2011 - Elsevier
As the gatekeepers of the eukaryotic cell nucleus, nuclear pore complexes (NPCs) mediate
all molecular trafficking between the nucleoplasm and the cytoplasm. In recent years …
all molecular trafficking between the nucleoplasm and the cytoplasm. In recent years …
The role of nuclear pores in gene regulation, development and disease
M Capelson, MW Hetzer - EMBO reports, 2009 - embopress.org
Nuclear‐pore complexes (NPCs) are large protein channels that span the nuclear envelope
(NE), which is a double membrane that encloses the nuclear genome of eukaryotes. Each of …
(NE), which is a double membrane that encloses the nuclear genome of eukaryotes. Each of …
The nuclear pore complex and the genome: organizing and regulatory principles
P Pascual-Garcia, M Capelson - Current opinion in genetics & …, 2021 - Elsevier
The nuclear pore complex (NPC) is a massive nuclear envelope-embedded protein
complex, the canonical function of which is to mediate selective nucleocytoplasmic transport …
complex, the canonical function of which is to mediate selective nucleocytoplasmic transport …
The multifunctional nuclear pore complex: a platform for controlling gene expression
C Ptak, JD Aitchison, RW Wozniak - Current opinion in cell biology, 2014 - Elsevier
In addition to their established roles in nucleocytoplasmic transport, the intimate association
of nuclear pore complexes (NPCs) with chromatin has long led to speculation that these …
of nuclear pore complexes (NPCs) with chromatin has long led to speculation that these …
One ring to rule them all? Structural and functional diversity in the nuclear pore complex
J Fernandez-Martinez, MP Rout - Trends in biochemical sciences, 2021 - cell.com
The nuclear pore complex (NPC) is the massive protein assembly that regulates the
transport of macromolecules between the nucleus and the cytoplasm. Recent breakthroughs …
transport of macromolecules between the nucleus and the cytoplasm. Recent breakthroughs …
Dynamics of nuclear pore complex organization through the cell cycle
In eukaryotic cells, all macromolecules that traffic between the nucleus and the cytoplasm
cross the double nuclear membrane through nuclear pore complexes (NPCs). NPCs are …
cross the double nuclear membrane through nuclear pore complexes (NPCs). NPCs are …
[PDF][PDF] Acting out of character: regulatory roles of nuclear pore complex proteins
N Xylourgidis, M Fornerod - Developmental cell, 2009 - cell.com
Nuclear pore complexes (NPCs) mediate all selective bidirectional transport between the
nucleus and the cytoplasm. Additional functions for NPCs and their constituent proteins …
nucleus and the cytoplasm. Additional functions for NPCs and their constituent proteins …
Dynamics and diverse functions of nuclear pore complex proteins
G Chatel, B Fahrenkrog - Nucleus, 2012 - Taylor & Francis
Nuclear pore complexes (NPCs) are best known for their central role in controlling the
molecular trafficking between the cytoplasm and the nucleus. NPCs are assembled from …
molecular trafficking between the cytoplasm and the nucleus. NPCs are assembled from …