In the story of human breast cancer, two major findings markedly modified the clinical
approach to treatment. Both belong to endocrinology. The first brought to light the hormone …

BACKGROUND Having observed that progesterone receptors exist in all gastric carcinoma
tissues, the authors determined that serum progesterone levels in gastric carcinoma patients …

We have examined the tissue-specific mRNA expression pattern of androgen receptor (AR),
both estrogen receptor (ER) subtypes ERα and ERβ and progestin receptor (PR) in 10 …

We have previously reported mitogenic effects of gastrin on a mouse colon cancer (MC-26)
cell line in vivo. The present studies were undertaken to determine if gonadal hormones can …

Background Sex steroid hormones influence function of the human gastrointestinal tract.
Although the specific receptor proteins have been identified in surgical specimens of both …

Some human ovarian malignancies respond favorably to hormone therapy. In order to
obtain more information about the endocrine properties of these malignancies, we …

The demonstration of two types of estrogen receptors (ER-alpha and-beta) and products of
estrogenrelated genes in gastrointestinal mucosa suggests that they may have a direct role …

Abstract Knowledge of the tumor content of estrogen (ER) and progesterone (PgR) receptors
has proved to be of significant value in human breast cancer. Relative determinations were …

Colorectal cancer (CRC) is a common malignancy in both genders with a high death rate,
accounting for about 56,000 each year in the USA only. In this study we examined the …