Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing
Z Xue, K Huang, C Cai, L Cai, C Jiang, Y Feng, Z Liu… - Nature, 2013 - nature.com
Mammalian pre-implantation development is a complex process involving dramatic changes
in the transcriptional architecture,,,. We report here a comprehensive analysis of …
in the transcriptional architecture,,,. We report here a comprehensive analysis of …
Protein expression landscape of mouse embryos during pre-implantation development
Y Gao, X Liu, B Tang, C Li, Z Kou, L Li, W Liu, Y Wu… - Cell reports, 2017 - cell.com
Pre-implantation embryo development is an intricate and precisely regulated process
orchestrated by maternally inherited proteins and newly synthesized proteins following …
orchestrated by maternally inherited proteins and newly synthesized proteins following …
Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development
The mouse embryo is the canonical model for mammalian preimplantation development.
Recent advances in single cell profiling allow detailed analysis of embryogenesis in other …
Recent advances in single cell profiling allow detailed analysis of embryogenesis in other …
Molecular architecture of lineage allocation and tissue organization in early mouse embryo
During post-implantation development of the mouse embryo, descendants of the inner cell
mass in the early epiblast transit from the naive to primed pluripotent state. Concurrently …
mass in the early epiblast transit from the naive to primed pluripotent state. Concurrently …
The unique transcriptome through day 3 of human preimplantation development
AT Dobson, R Raja, MJ Abeyta, T Taylor… - Human molecular …, 2004 - academic.oup.com
Successful human development is dependent upon a cascade of events following
fertilization. Unfortunately, knowledge of these critical events in humans is remarkably …
fertilization. Unfortunately, knowledge of these critical events in humans is remarkably …
A genome-wide study of gene activity reveals developmental signaling pathways in the preimplantation mouse embryo
QT Wang, K Piotrowska, MA Ciemerych, L Milenkovic… - Developmental cell, 2004 - cell.com
The preimplantation development of the mammalian embryo encompasses a series of
critical events: the transition from oocyte to embryo, the first cell divisions, the establishment …
critical events: the transition from oocyte to embryo, the first cell divisions, the establishment …
Technical challenges of studying early human development
PJ Rugg-Gunn, N Moris, PPL Tam - Development, 2023 - journals.biologists.com
Recent years have seen exciting progress across human embryo research, including new
methods for culturing embryos, transcriptional profiling of embryogenesis and gastrulation …
methods for culturing embryos, transcriptional profiling of embryogenesis and gastrulation …
Isoform-resolved transcriptome of the human preimplantation embryo
D Torre, NJ Francoeur, Y Kalma, I Gross Carmel… - Nature …, 2023 - nature.com
Human preimplantation development involves extensive remodeling of RNA expression and
splicing. However, its transcriptome has been compiled using short-read sequencing data …
splicing. However, its transcriptome has been compiled using short-read sequencing data …
Human embryogenesis: a comparative perspective
C Gerri, S Menchero, SK Mahadevaiah… - Annual review of cell …, 2020 - annualreviews.org
Understanding human embryology has historically relied on comparative approaches using
mammalian model organisms. With the advent of low-input methods to investigate genetic …
mammalian model organisms. With the advent of low-input methods to investigate genetic …
Systematic reconstruction of cellular trajectories across mouse embryogenesis
Mammalian embryogenesis is characterized by rapid cellular proliferation and
diversification. Within a few weeks, a single-cell zygote gives rise to millions of cells …
diversification. Within a few weeks, a single-cell zygote gives rise to millions of cells …