Structure and function of adenosine receptors and their genes

BB Fredholm, G Arslan, L Halldner, B Kull… - Naunyn-Schmiedeberg's …, 2000 - Springer
Four adenosine receptors have been cloned from many mammalian and some non-
mammalian species. In each case the translated part of the receptor is encoded by two …

Structure and function of A1 adenosine receptors1

J Linden - The FASEB journal, 1991 - Wiley Online Library
The A1 adenosine receptor is the best characterized of the widely distributed purinergic
receptor family. The purified brain A1 receptor is a monomeric 35‐to 36‐kDa glycoprotein …

Adenosine receptors and their ligands

KN Klotz - Naunyn-Schmiedeberg's archives of pharmacology, 2000 - Springer
The regulatory actions of adenosine are mediated via four subtypes of G protein-coupled
receptors distinguished as A 1, A 2A, A 2B and A 3 receptors. Their presence on basically …

Adenosine receptors: new opportunities for future drugs

SA Poulsen, RJ Quinn - Bioorganic & medicinal chemistry, 1998 - Elsevier
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International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors

BB Fredholm, AP IJzerman, KA Jacobson… - Pharmacological …, 2001 - ASPET
Four adenosine receptors have been cloned and characterized from several mammalian
species. The receptors are named adenosine A1, A2A, A2B, and A3. The A2A and A2B …

Adenosine receptors: G protein-mediated signalling and the role of accessory proteins

M Klinger, M Freissmuth, C Nanoff - Cellular signalling, 2002 - Elsevier
Ever since the discovery of the effects of adenosine in the circulation, adenosine receptors
continue to represent a promising drug target. Firstly, this is due to the fact that the receptors …

Comparative pharmacology of human adenosine receptor subtypes–characterization of stably transfected receptors in CHO cells

KN Klotz, J Hessling, J Hegler, C Owman, B Kull… - Naunyn-Schmiedeberg's …, 1997 - Springer
Four adenosine receptor subtypes of the family of G protein-coupled receptors, designated A
1, A 2A, A 2B and A 3 are currently known. In this study all human subtypes were stably …

Animal models for the study of adenosine receptor function

R Yaar, MR Jones, JF Chen… - Journal of cellular …, 2005 - Wiley Online Library
Adenosine receptors represent a family of G‐protein coupled receptors that are ubiquitously
expressed in a wide variety of tissues. This family contains four receptor subtypes: A1 and …

Adenosine receptor subtypes: characterization and therapeutic regulation.

ME Olah, GL Stiles - Annual review of pharmacology and toxicology, 1995 - europepmc.org
Adenosine receptors (ARs) are members of the G protein-coupled receptor family and
mediate the multiple physiological effects of adenosine. Currently, four AR subtypes have …

[HTML][HTML] Site-directed Mutagenesis Identifies Residues Involved in Ligand Recognition in the Human A2a Adenosine Receptor∗

J Kim, J Wess, AM van Rhee, T Schöneberg… - Journal of Biological …, 1995 - ASBMB
The A 2a adenosine receptor is a member of the G-protein coupled receptor family, and its
activation stimulates cyclic AMP production. To determine the residues which are involved in …