p38 mitogen-activated protein kinase (MAPK) activates a number of heat shock proteins
(HSPs), including HSP27 and αB-crystallin, in response to stress. Activation of HSP27 or αB …

Both p38 mitogen-activated protein kinase (p38) activation and protein kinase B (Akt)
activation have been reported to regulate glucose transport during myocardial I/R. An …

Although 17β-estradiol (E2) administration following trauma-hemorrhage (TH) improves
cardiac function in male rodents, it is not known whether the salutary effects of E2 are …

Studies have shown that p38 MAPK and nitric oxide (NO), generated by endothelial NO
synthase (eNOS), play key roles under physiological and pathophysiological conditions …

Objectives: Because administration of 17β-estradiol following trauma-hemorrhage improves
cardiovascular responses, we investigated whether the salutary effects of 17β-estradiol on …

Abstract Although 17β-estradiol (estrogen) and estrogen receptor (ER) agonist
administration after trauma-hemorrhage improves cardiac function, it remains unknown what …

Although several studies have shown that the administration of 17β-estradiol (estrogen) is
cardioprotective to ischemia-reperfusion (I/R), the molecular mechanisms are largely …

Objective: To determine whether the nongenomic actions of E2 have any beneficial effect on
cardiac function following trauma-hemorrhage and whether those effects are mediated via …

From human and animal studies, estrogen is known to protect the myocardium from an
ischemic insult. However, there is limited knowledge regarding mechanisms by which …

Although studies indicate that 17β-estradiol administration after trauma-hemorrhage (TH)
improves cardiac and hepatic functions, the underlying mechanisms remain unclear …