Causes and consequences of cerebral small vessel disease. The RUN DMC study: a prospective cohort study. Study rationale and protocol

AGW van Norden, KF de Laat, RAR Gons… - BMC neurology, 2011 - Springer
Background Cerebral small vessel disease (SVD) is a frequent finding on CT and MRI scans
of elderly people and is related to vascular risk factors and cognitive and motor impairment …

New insights into cerebral small vessel disease and vascular cognitive impairment from MRI

EE Smith, AE Beaudin - Current opinion in neurology, 2018 - journals.lww.com
New insights into cerebral small vessel disease and vascular... : Current Opinion in Neurology
New insights into cerebral small vessel disease and vascular cognitive impairment from MRI …

Factors associated with 8-year mortality in older patients with cerebral small vessel disease: the Radboud University Nijmegen Diffusion Tensor and Magnetic …

HM van der Holst, IWM van Uden, AM Tuladhar… - JAMA …, 2016 - jamanetwork.com
Importance Gait and cognition have been related to mortality in population-based studies.
This association is possibly mediated by cerebral small vessel disease (SVD), which has …

[HTML][HTML] Diffusion tensor imaging and cognition in cerebral small vessel disease: the RUN DMC study

AGW van Norden, KF de Laat, EJ van Dijk… - … et Biophysica Acta (BBA …, 2012 - Elsevier
BACKGROUND: Cerebral small vessel disease (SVD) is very common in elderly and related
to cognition, although this relation is weak. This might be because the underlying pathology …

Cerebral small vessel disease: how does it progress?

K Schmidtke, M Hüll - Journal of the Neurological Sciences, 2005 - Elsevier
Small vessel disease (SVD), or microangiopathy, of the cerebral white and central grey
matter is an important subtype of vascular dementia (VD). SVD-dementia is characterised by …

Change in multimodal MRI markers predicts dementia risk in cerebral small vessel disease

EA Zeestraten, AJ Lawrence, C Lambert, P Benjamin… - Neurology, 2017 - AAN Enterprises
Objective: To determine whether MRI markers, including diffusion tensor imaging (DTI), can
predict cognitive decline and dementia in patients with cerebral small vessel disease (SVD) …

Advanced neuroimaging of cerebral small vessel disease

GW Blair, MV Hernandez, MJ Thrippleton… - … treatment options in …, 2017 - Springer
Opinion statement Cerebral small vessel disease (SVD) is characterised by damage to deep
grey and white matter structures of the brain and is responsible for a diverse range of clinical …

The contribution of small vessel disease to neurodegeneration: focus on Alzheimer's disease, Parkinson's disease and multiple sclerosis

F Paolini Paoletti, S Simoni, L Parnetti… - International journal of …, 2021 - mdpi.com
Brain small vessel disease (SVD) refers to a variety of structural and functional changes
affecting small arteries and micro vessels, and manifesting as white matter changes …

Current pathophysiological concepts in cerebral small vessel disease

F Rincon, CB Wright - Frontiers in aging neuroscience, 2014 - frontiersin.org
The association between cerebral small vessel disease (SVD)–in the form of white matter
lesions, infarctions, and hemorrhages–with vascular cognitive impairment (VCI), has mostly …

Simple MRI score aids prediction of dementia in cerebral small vessel disease

A Amin Al Olama, JMS Wason, AM Tuladhar… - Neurology, 2020 - AAN Enterprises
Objective To determine whether a simple small vessel disease (SVD) score, which uses
information available on rapid visual assessment of clinical MRI scans, predicts risk of …