Acute kidney injury (AKI) significantly contributes to morbidity and mortality in critically ill
patients. AKI is also an independent risk factor for the development and progression of …

Acute kidney injury (AKI) continues to be a significant contributor to morbidity, mortality, and
health care expenditure. In the United States alone, it is estimated that more than $10 billion …

Acute kidney injury (AKI) is a common clinical entity that is associated with high mortality and
morbidity. It is a risk factor for the development and progression of chronic kidney disease …

Recent studies show that it is now eminently feasible to pharmacologically manipulate
various key aspects of mitochondrial biology in the kidney, and this has much potential for …

Ischemia-reperfusion injury (IRI) is a common cause of acute kidney injury (AKI). The kidney
is susceptible to IRI under several clinical conditions, including hypotension, sepsis, and …

Acute kidney injury (AKI) is a serious clinical condition with no effective treatment. Tubular
cells are key targets in AKI. Tubular cells and, specifically, proximal tubular cells are …

Acute Kidney Injury (AKI), a critical clinical syndrome, has been strongly linked to
mitochondrial malfunction. Mitochondria, vital cellular organelles, play a key role in …

The kidney is a highly metabolic organ that requires substantial adenosine triphosphate for
the active transport required to maintain water and solute reabsorption. Aberrations in …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected conditions,
and CKD is projected to become the fifth leading global cause of death by 2040. New …

Abstract The kidneys compose approximately 0.5% of the body mass but consume about
10% of the oxygen in cellular respiration. This discordance is due to the high energy …