Cholangiocarcinoma (CC) worldwide is the most common biliary malignancy with poor
prognostic value and new systemic treatments are desirable. Plant extracts like bromelain …

Berberine is a natural compound found in several herbs. Anticancer activity of berberine was
reported in several cancers, however, little is known regarding the effects of berberine …

Background: Black pepper (Piper nigrum L.) is widely used as a traditional medicine,
including usage for pain relief, fevers, as well as an anticancer agent. Previously, we …

Background Intrahepatic cholangiocarcinoma (ICC) is a malignancy with a hidden onset,
high metastasis recurrence rate, and poor prognosis. Research on effective drugs for ICC is …

Background Magnolol has shown the potential anticancer properties against a variety of
cancers. However, the role of magnolol in cholangiocarcinoma (CCA) cells is unknown. In …

Background Bromelain is a pineapple stem extract with a variety of therapeutic benefits
arising from interaction with a number of different biological processes. Several preclinical …

The chemotherapeutic approach using non-toxic natural products may be one of the
strategies for the management of the cholangiocarcinoma. Here we report that in vitro …

Brusatol, isolated from brucea, has been proved to exhibit anticancer influence on various
kind of human malignancies. However, the role that brusatol plays in pancreatic cancer is …

Background and objectives: Pancreatic cancer is one of the most lethal cancer types.
Pancreatic cancer is highly malignant and characterized by rapid and uncontrolled growth …

Cholangiocarcinoma (CCA) is one of the most common causes of cancer‑associated
mortality in Thailand. Certain phytochemicals have been demonstrated to modulate …