Urinary bladder hyperreflexia: a rat animal model

H Shaker, MS Mourad, MH Elbialy… - … : Official Journal of the …, 2003 - Wiley Online Library
In this work, we are presenting a rat animal model for bladder hyperreflexia after suprasacral
spinal cord transection. Our aim was to standardize an animal model that can be useful in …

Changes in micturition after spinal cord injury in conscious rats

M Yoshiyama, FM Nezu, O Yokoyama, WC de Groat… - Urology, 1999 - Elsevier
Objectives. To determine the feasibility of urodynamic monitoring of voiding function in
conscious, female spinal cord-injured (SCI) rats and to compare the voiding function in SCI …

Functional improvement in spinal cord injury-induced neurogenic bladder by bladder augmentation using bladder acellular matrix graft in the rat

S Urakami, H Shiina, H Enokida, K Kawamoto… - World journal of …, 2007 - Springer
Spinal cord injury (SCI) rostral to the lumbosacral level causes bladder hyperreflexia and
detrusor-sphincter dyssynergia (DSD), which are accompanied by bladder hypertrophy. We …

Effect of urinary diversion on the recovery of micturition reflexes after spinal cord injury in the rat

MN Kruse, B Bennett, WC De Groat - The Journal of urology, 1994 - Elsevier
Patients with suprasacral spinal cord injury usually exhibit severe lower urinary tract
dysfunction, which is generally attributed to loss of supraspinal input to the spinal micturition …

An artificial somatic-central nervous system-autonomic reflex pathway for controllable micturition after spinal cord injury: preliminary results in 15 patients

CG Xiao, MX Du, C Dai, B Li, VW Nitti… - The Journal of …, 2003 - auajournals.org
Purpose: Neurogenic bladder dysfunction after spinal cord injury (SCI) is a major medical
and social problem for which there is no definitive solution. After the successful …

An animal model for the neuromodulation of neurogenic bladder dysfunction

Zvara, Sahi, Hassouna - British journal of urology, 1998 - Wiley Online Library
Objective To develop an animal model to examine the pathophysiology by which S3 sacral
root electrostimulation alters the micturition reflex in patients with bladder hyper‐reflexia …

Bladder afferent pathway and spinal cord injury: possible mechanisms inducing hyperreflexia of the urinary bladder

N Yoshimura - Progress in neurobiology, 1999 - Elsevier
Lower urinary tract dysfunction is a common problem in patients with spinal cord injury (SCI).
Since the coordination of the urinary bladder and urethra is controlled by the complex …

Inhibiting the hyperreflexic bladder with electrical stimulation in a spinal animal model

JS Walter, JS Wheeler, CJ Robinson… - Neurourology and …, 1993 - Wiley Online Library
Uninhibited bladder contractions are a problem in spinal cord injured patients. Accordingly,
methods using electrical stimulation to inhibit the bladder were investigated in chronic spinal …

Hyperreflexia of the urinary bladder: possible role of the efferent function of the capsaicin sensitive primary afferents

HS SHAKER, LEMAI TU, M KALFOPOULOS… - The Journal of …, 1998 - auajournals.org
Purpose: Capsaicin sensitive primary afferents (CSPA) have been implicated in the
pathogenesis hyperreflexia after spinalization. In this study we investigated the role of the …

Urinary bladder response to hypogastric nerve stimulation after bilateral resection of the pelvic nerve or spinal cord injury in rats

H Kontani, K Hayashi - International journal of urology, 1997 - Wiley Online Library
Background: We examined the mechanism of urinary bladder motility return after bladder
areflexia induced by interruption of the sacral parasympathetic outflow to the urinary bladder …