Accumulation of adiponectin in inflamed adipose tissues of obese mice

H Nakatsuji, K Kishida, R Sekimoto, N Komura… - Metabolism, 2014 - Elsevier
Objective Adipose tissue inflammation plays an important role in the pathogenesis of obesity-
associated complications, such as atherosclerosis. Adiponectin secreted from adipocytes …

Elevated adiponectin expression promotes adipose tissue vascularity under conditions of diet-induced obesity

TR Aprahamian - Metabolism, 2013 - Elsevier
Objective Despite the clinical prevalence of obesity, only recently has the importance of
adipose tissue microenvironment been addressed at a molecular level. Here, I focused on …

[HTML][HTML] Tracing the movement of adiponectin in a parabiosis model of wild-type and adiponectin-knockout mice

H Nakatsuji, K Kishida, R Sekimoto, T Funahashi… - FEBS Open Bio, 2014 - Elsevier
Adiponectin is exclusively synthesized by adipocytes and exhibits anti-diabetic, anti-
atherosclerotic and anti-inflammatory properties. Hypoadiponectinemia is associated in …

[HTML][HTML] Adiponectin protein exists in aortic endothelial cells

N Komura, N Maeda, T Mori, S Kihara, H Nakatsuji… - PloS one, 2013 - journals.plos.org
Aims Inflammation is closely associated with the development of atherosclerosis and
metabolic syndrome. Adiponectin, an adipose-derived secretory protein, possesses an anti …

Adiponectin: a link between excess adiposity and associated comorbidities?

O Ukkola, M Santaniemi - Journal of molecular medicine, 2002 - Springer
Adiponectin is a novel polypeptide that is highly specific to adipose tissue. In contrast to
other adipocytokines, adiponectin levels are decreased in obesity and associated …

Adiponectin suppresses inflammatory responses at the early phase of atherosclerosis in hyperglycemic rats

JB Liu, L Jia, BR Li, LZ Lan, Q Ge… - Molecular …, 2010 - spandidos-publications.com
Adiponectin plays an important role in atherosclerosis, but its relationship with the early
initiation of atherosclerosis in diabetes mellitus is still not completely understood. In this …

Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin

WS Yang, WJ Lee, T Funahashi… - The Journal of …, 2001 - academic.oup.com
Adiponectin, an adipose tissue-specific plasma protein, was recently revealed to have anti-
inflammatory effects on the cellular components of vascular wall. Its plasma levels were …

[HTML][HTML] Disruption of adiponectin causes insulin resistance and neointimal formation

N Kubota, Y Terauchi, T Yamauchi, T Kubota… - Journal of biological …, 2002 - ASBMB
The adipocyte-derived hormone adiponectin has been proposed to play important roles in
the regulation of energy homeostasis and insulin sensitivity, and it has been reported to …

[HTML][HTML] Ultrastructural localization of adiponectin protein in vasculature of normal and atherosclerotic mice

T Mori, Y Koyama, N Maeda, Y Nakamura… - Scientific reports, 2014 - nature.com
Adiponectin, adipose-specific secretory protein, abundantly circulates in bloodstream and its
concentration is around 1000-fold higher than that of other cytokines and hormones …

Effects of macrophage-specific adiponectin expression on lipid metabolism in vivo

N Luo, X Wang, BH Chung, MH Lee… - American Journal …, 2011 - journals.physiology.org
Epidemiological studies have associated low circulating levels of the adipokine adiponectin
with multiple metabolic disorders, including metabolic syndrome, obesity, insulin resistance …