Obesity is a major driving factor in the incidence, progression, and poor treatment response
in gastrointestinal cancers. Herein, we conducted a comprehensive analysis of the impact of …

Excess adiposity is a risk factor for several cancers of the gastrointestinal system, specifically
oesophageal adenocarcinoma and colorectal, small intestine, pancreatic, liver, gallbladder …

Increasing recognition of an association between obesity and many cancer types exists, but
how the myriad of local and systemic effects of obesity affect key cellular and non-cellular …

Obesity and its associated metabolic dysregulation are established risk factors for many
cancers. However, the biologic mechanisms underlying this relationship remain …

Obesity is a risk factor for all major gastrointestinal cancers. With the rapid increase in the
prevalence of obesity worldwide, this link could lead to an elevated burden of cancers of the …

Obesity-associated diseases account for a large portion of public health challenges. Among
obesity-related disorders, a direct and independent relationship has been ascertained for …

Obesity and obesity-related disorders such as non-alcoholic fatty liver disease (NAFLD),
metabolic syndrome and type 2 diabetes exhibit an increased risk of developing various …

Colorectal cancer (CRC) is a major health problem worldwide, with an estimated 1.9 million
new cases and 915,880 deaths in 2020 alone. The etiology of CRC is complex and involves …

The incidence of obesity, a leading modifiable risk factor for common solid tumors, is
increasing. Effective interventions are needed to minimize the public health implications of …

Purpose There is growing evidence that inflammation is a central and reversible mechanism
through which obesity promotes cancer risk and progression. Methods We review recent …