Ultraviolet (UV) radiation is one of the most important environmental factors involved in the
pathogenesis of premature skin ageing, termed photoageing. The harmful effects of UV in …

UV radiation is an important environmental factor in the pathogenesis of skin aging and
cancer. Many harmful effects of UV radiation are associated with generation of reactive …

Abstract The KEAP1 (Kelch-like ECH-associated protein 1)-NRF2 (NF-E2-related factor 2)
system controls the biochemical defense activity against agents toxic to mammals and …

Ultraviolet (UV) radiation is one of the most important environmental factors involved in the
pathogenesis of skin aging and cancer. Many harmful effects of UV radiation are associated …

Nrf2 plays a critical role in defending against oxidative stress and inflammation. We
previously reported that Nrf2 confers protection against ultraviolet-B (UVB)-induced …

Ultraviolet (UV) of sunlight is a complete carcinogen that can burn skin, enhance
inflammation, and drive skin carcinogenesis. Previously, we have shown that sulforaphane …

Background. Skin photodamage is associated with ultraviolet‐(UV‐) induced reactive
oxygen species (ROS) overproduction and nuclear factor erythroid 2‐related factor 2 (Nrf2) …

UVA irradiation plays a role in premature aging of the skin through triggering oxidative stress-
associated stimulation of matrix metalloproteinase-1 (MMP-1) responsible for collagen …

Summary Ultraviolet A (UVA, 320-400 nm) radiation is an oxidizing agent that causes
significant damage to cellular components and that leads to photoaging and cancer. It …

The skin barrier and its endogenous protective mechanisms cope daily with exogenous
stressors, of which ultraviolet radiation (UVR) poses an imminent danger. Although the skin …