Circulating tumor cell–based molecular classifier for predicting resistance to abiraterone and enzalutamide in metastatic castration-resistant prostate cancer
While circulating tumor cell (CTC)–based detection of AR-V7 has been demonstrated to
predict patient response to second-generation androgen receptor therapies, the rarity of AR …
predict patient response to second-generation androgen receptor therapies, the rarity of AR …
AR‐V7 in circulating tumor cells cluster as a predictive biomarker of abiraterone acetate and enzalutamide treatment in castration‐resistant prostate cancer patients
T Okegawa, N Ninomiya, K Masuda, Y Nakamura… - The …, 2018 - Wiley Online Library
Objective We examined whether androgen receptor splice variant 7 (AR‐V7) in circulating
tumor cell (CTC) clusters can be used to predict survival in patients with bone metastatic …
tumor cell (CTC) clusters can be used to predict survival in patients with bone metastatic …
Prospective multicenter study of circulating tumor cell AR-V7 and taxane versus hormonal treatment outcomes in metastatic castration-resistant prostate cancer
AJ Armstrong, J Luo, DM Nanus… - JCO precision …, 2020 - ascopubs.org
PURPOSE Androgen receptor splice variant 7 (AR-V7) detection in circulating tumor cells
(CTCs) is associated with a low probability of response and short progression-free (PFS) …
(CTCs) is associated with a low probability of response and short progression-free (PFS) …
[HTML][HTML] Nuclear-specific AR-V7 protein localization is necessary to guide treatment selection in metastatic castration-resistant prostate cancer
Abstract Background Circulating tumor cells (CTCs) expressing AR-V7 protein localized to
the nucleus (nuclear-specific) identify metastatic castration-resistant prostate cancer …
the nucleus (nuclear-specific) identify metastatic castration-resistant prostate cancer …
Comparison of circulating tumor cells and AR-V7 as clinical biomarker in metastatic castration-resistant prostate cancer patients
K Schlack, K Seitzer, N Wüstmann, V Humberg… - Scientific Reports, 2022 - nature.com
Biomarker in metastatic castration resistant prostate cancer (mCRPC) treatment are rare. We
aimed to compare the clinical value of circulating tumor cells (CTCs) and androgen receptor …
aimed to compare the clinical value of circulating tumor cells (CTCs) and androgen receptor …
Analysis of AR/ARV7 expression in isolated circulating tumor cells of patients with metastatic castration-resistant prostate cancer (SAKK 08/14 IMPROVE Trial)
I Bratic Hench, R Cathomas, L Costa, N Fischer… - Cancers, 2019 - mdpi.com
Despite several treatment options and an initial high response rate to androgen deprivation
therapy, the majority of prostate cancers will eventually become castration-resistant in the …
therapy, the majority of prostate cancers will eventually become castration-resistant in the …
Clinical significance of androgen receptor splice variant-7 mRNA detection in circulating tumor cells of men with metastatic castration-resistant prostate cancer treated …
Purpose We reported previously that the detection of androgen receptor splice variant-7 (AR-
V7) mRNA in circulating tumor cells (CTCs) correlated with poor outcomes from the use of …
V7) mRNA in circulating tumor cells (CTCs) correlated with poor outcomes from the use of …
[HTML][HTML] CABA-V7: a prospective biomarker selected trial of cabazitaxel treatment in AR-V7 positive prostate cancer patients
KT Isebia, B Mostert, BPS Belderbos, SAJ Buck… - European Journal of …, 2022 - Elsevier
Background Metastatic castration-resistant prostate cancer (mCRPC) patients with positive
AR-V7 expression in their circulating tumour cells (CTCs) rarely derive benefit from …
AR-V7 expression in their circulating tumour cells (CTCs) rarely derive benefit from …
AR-V7 in peripheral whole blood of patients with castration-resistant prostate cancer: association with treatment-specific outcome under abiraterone and enzalutamide
AK Seitz, S Thoene, A Bietenbeck, R Nawroth… - European urology, 2017 - Elsevier
Background It has been demonstrated that androgen receptor splice variant 7 (AR-V7)
expression in circulating tumor cells (CTCs) predicts poor treatment response in metastatic …
expression in circulating tumor cells (CTCs) predicts poor treatment response in metastatic …
[HTML][HTML] Serial blood-based analysis of AR-V7 in men with advanced prostate cancer
M Nakazawa, C Lu, Y Chen, CJ Paller, MA Carducci… - Annals of …, 2015 - Elsevier
Background We previously showed that pretreatment detection of androgen receptor splice
variant-7 (AR-V7) in circulating tumor cells (CTCs) from men with castration-resistant …
variant-7 (AR-V7) in circulating tumor cells (CTCs) from men with castration-resistant …
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