Challenges of nanoparticle albumin bound (nab™) technology: Comparative study of Abraxane® with a newly developed albumin-stabilized itraconazole …
A Adick, W Hoheisel, S Schneid, D Mulac… - European Journal of …, 2023 - Elsevier
Nanoparticle albumin bound™(nab™) technology is an established delivery platform for
development of albumin stabilized nanoparticles as drug delivery systems for poorly water …
development of albumin stabilized nanoparticles as drug delivery systems for poorly water …
Rational design of nanocarriers for intracellular protein delivery
Protein/antibody therapeutics have exhibited the advantages of high specificity and activity
even at an extremely low concentration compared to small molecule drugs. However, they …
even at an extremely low concentration compared to small molecule drugs. However, they …
Targeted delivery of protein drugs by nanocarriers
R Solaro, F Chiellini, A Battisti - Materials, 2010 - mdpi.com
Recent advances in biotechnology demonstrate that peptides and proteins are the basis of a
new generation of drugs. However, the transportation of protein drugs in the body is limited …
new generation of drugs. However, the transportation of protein drugs in the body is limited …
[HTML][HTML] In vivo biocompatibility, clearance, and biodistribution of albumin vehicles for pulmonary drug delivery
A Woods, A Patel, D Spina, Y Riffo-Vasquez… - Journal of Controlled …, 2015 - Elsevier
The development of clinically acceptable albumin-based nanoparticle formulations for use in
pulmonary drug delivery has been hindered by concerns about the toxicity of nanomaterials …
pulmonary drug delivery has been hindered by concerns about the toxicity of nanomaterials …
Dual-targeted nano-in-nano albumin carriers enhance the efficacy of combined chemo/herbal therapy of lung cancer
MM Elgohary, MW Helmy, SM Mortada… - Nanomedicine, 2018 - Taylor & Francis
Aim: A Nano-in-Nano approach was exploited to facilitate incorporation of the
chemotherapeutic drug etoposide (ETP) as nanosuspension, synergistically with berberine …
chemotherapeutic drug etoposide (ETP) as nanosuspension, synergistically with berberine …
Doxorubicin-loaded, pH-sensitive albumin nanoparticles for lung cancer cell targeting
In recent decades, scientific and medical communities have continuously sought new
methods and chemistries to improve the treatment of cancer. Among many types of …
methods and chemistries to improve the treatment of cancer. Among many types of …
Nanotechnology-based drug delivery systems: challenges and opportunities
There is a need of a carrier that can deliver drugs to the targeted cells and organs, where it
can prolong and localize its effect, interacting with the diseased part of the organ specifically …
can prolong and localize its effect, interacting with the diseased part of the organ specifically …
Nanoparticles in drug delivery: potential green nanobiomedicine applications
R Ravichandran - International Journal of Green Nanotechnology …, 2009 - Taylor & Francis
One of the most challenging tasks for formulators in the pharmaceutical industry is the
formulation of poorly soluble drugs. Conventional techniques employed for improving …
formulation of poorly soluble drugs. Conventional techniques employed for improving …
Multifunctional albumin nanoparticles as combination drug carriers for intra‐tumoral chemotherapy
M Cui, DJ Naczynski, M Zevon… - Advanced …, 2013 - Wiley Online Library
Current cancer therapies are challenged by weakly soluble drugs and by drug combinations
that exhibit non‐uniform biodistribution and poor bioavailability. In this study, we have …
that exhibit non‐uniform biodistribution and poor bioavailability. In this study, we have …
[HTML][HTML] Designing nanoparticle-based drug delivery systems for precision medicine
J Yang, C Jia, J Yang - International journal of medical sciences, 2021 - ncbi.nlm.nih.gov
Traditional drugs are facing bottlenecks of lower solubility, absorption, and especially the
inefficient organs or cells targeting during the precision medicine era. It is urgently needed to …
inefficient organs or cells targeting during the precision medicine era. It is urgently needed to …