Challenges of nanoparticle albumin bound (nab™) technology: Comparative study of Abraxane® with a newly developed albumin-stabilized itraconazole …

A Adick, W Hoheisel, S Schneid, D Mulac… - European Journal of …, 2023 - Elsevier
Nanoparticle albumin bound™(nab™) technology is an established delivery platform for
development of albumin stabilized nanoparticles as drug delivery systems for poorly water …

Rational design of nanocarriers for intracellular protein delivery

X Qin, C Yu, J Wei, L Li, C Zhang, Q Wu… - Advanced …, 2019 - Wiley Online Library
Protein/antibody therapeutics have exhibited the advantages of high specificity and activity
even at an extremely low concentration compared to small molecule drugs. However, they …

Targeted delivery of protein drugs by nanocarriers

R Solaro, F Chiellini, A Battisti - Materials, 2010 - mdpi.com
Recent advances in biotechnology demonstrate that peptides and proteins are the basis of a
new generation of drugs. However, the transportation of protein drugs in the body is limited …

[HTML][HTML] In vivo biocompatibility, clearance, and biodistribution of albumin vehicles for pulmonary drug delivery

A Woods, A Patel, D Spina, Y Riffo-Vasquez… - Journal of Controlled …, 2015 - Elsevier
The development of clinically acceptable albumin-based nanoparticle formulations for use in
pulmonary drug delivery has been hindered by concerns about the toxicity of nanomaterials …

Dual-targeted nano-in-nano albumin carriers enhance the efficacy of combined chemo/herbal therapy of lung cancer

MM Elgohary, MW Helmy, SM Mortada… - Nanomedicine, 2018 - Taylor & Francis
Aim: A Nano-in-Nano approach was exploited to facilitate incorporation of the
chemotherapeutic drug etoposide (ETP) as nanosuspension, synergistically with berberine …

Doxorubicin-loaded, pH-sensitive albumin nanoparticles for lung cancer cell targeting

A Aziz, Y Sefidbakht, S Rezaei… - Journal of …, 2022 - Elsevier
In recent decades, scientific and medical communities have continuously sought new
methods and chemistries to improve the treatment of cancer. Among many types of …

Nanotechnology-based drug delivery systems: challenges and opportunities

D Sharma, N Sharma, M Pathak, PK Agrawala… - Drug targeting and …, 2018 - Elsevier
There is a need of a carrier that can deliver drugs to the targeted cells and organs, where it
can prolong and localize its effect, interacting with the diseased part of the organ specifically …

Nanoparticles in drug delivery: potential green nanobiomedicine applications

R Ravichandran - International Journal of Green Nanotechnology …, 2009 - Taylor & Francis
One of the most challenging tasks for formulators in the pharmaceutical industry is the
formulation of poorly soluble drugs. Conventional techniques employed for improving …

Multifunctional albumin nanoparticles as combination drug carriers for intra‐tumoral chemotherapy

M Cui, DJ Naczynski, M Zevon… - Advanced …, 2013 - Wiley Online Library
Current cancer therapies are challenged by weakly soluble drugs and by drug combinations
that exhibit non‐uniform biodistribution and poor bioavailability. In this study, we have …

[HTML][HTML] Designing nanoparticle-based drug delivery systems for precision medicine

J Yang, C Jia, J Yang - International journal of medical sciences, 2021 - ncbi.nlm.nih.gov
Traditional drugs are facing bottlenecks of lower solubility, absorption, and especially the
inefficient organs or cells targeting during the precision medicine era. It is urgently needed to …