Pyroptosis is a programmed cell death mode discovered in recent years. It is caused by
inflammasomes and the perforation of Gasdermin family proteins, and results in the release …

Pyroptosis is a form of programmed cell death associated with activation of inflammasomes
and inflammatory caspases, proteolytic cleavage of gasdermin proteins (forming pores in the …

Pyroptosis is mainly considered as a new pro-inflammatory mediated-programmed cell
death. In addition, pyroptosis is described by gasdermin-induced pore formation on the …

Pyroptosis is a pattern of programmed cell death that significantly differs from apoptosis and
autophagy in terms of cell morphology and function. The process of pyroptosis is …

Cardiac function is determined by the dynamic equilibrium of various cell types and the
extracellular matrix that composes the heart. Cardiovascular diseases (CVDs), especially …

Pyroptosis is known as a novel form of pro-inflammatory cell death program, which is
exceptional from other types of cell death programs. Particularly, pyroptosis is characterized …

Pyroptosis is an inflammatory form of cell death triggered by certain inflammasomes, leading
to the cleavage of gasdermin D (GSDMD) and activation of inactive cytokines like IL-18 and …

Programmed cell deaths are pathways involving cells playing an active role in their own
destruction. Depending on the signaling system of the process, programmed cell death can …

Cell death and inflammation are the fundamental biological processes in both normal
physiology and pathology. Apoptosis is the most well-studied process of cell death, but there …

Pyroptosis is a kind of programmed cell death closely related to inflammation. The pathways
that mediate pyroptosis can be divided into the Caspase-1-dependent canonical pathway …