Diabetic cardiomyopathy (DCM), a serious diabetic complication, is a kind of low-grade
inflammatory cardiovascular disorder. Due to the high risk of morbidity and mortality, DCM …

Rationale: Pyroptosis is a morphologically and mechanistically distinct form of cell death and
is characterized by GSDMD (gasdermin D) or GSDME (gasdermin E)-mediated necrosis …

Pyroptosis is a novel programmed cell death form which is distinct from other types of cell
death. As an inherently inflammatory process, it plays a vital role in cellular lysis and release …

Pyroptosis, a lytic pro-inflammatory type of programmed cell death, has been widely studied
in diverse inflammatory disease models. Membrane perforation and cell swelling induced by …

Programmed Cell Death (PCD) is considered to be a pathological form of cell death when
mediated by an intracellular program and it balances cell death with survival of normal cells …

Pyroptosis is a controlled form of inflammatory cell death characterized by inflammasome
activation, pore formation, and cell lysis. According to different caspases, pyroptosis can be …

Fibrosis is responsible for approximately 45% of deaths in the industrialized world and has
been a major global healthcare burden. Excessive fibrosis is the primary cause of organ …

Programmed cell death (PCD) refers to the way in which cells die depending on specific
genes encoding signals or activities. Apoptosis, autophagy, and pyroptosis are all …

Pyroptosis, a type of inflammatory programmed cell death, is triggered by caspase cleavage
of gasdermin family proteins. Based on accumulating evidence, pyroptosis is closely …

Pyroptosis is commonly induced by the gasdermin (GSDM) family and is accompanied by
the release of inflammatory cytokines such as IL-1β and IL-18. Recently, increasing …