Pyroptosis is a newly discovered programmed cell death with inflammasome formation.
Pattern recognition receptors that identify repetitive motifs of prospective pathogens such as …

Pyroptosis is a programmed cell death characterized by swift plasma membrane disruption
and subsequent release of cellular contents and pro-inflammatory mediators (cytokines) …

Chemotherapy drugs usually inhibit tumor cell growth through the apoptosis pathway.
However, tumor cells become resistant to chemotherapy drugs by evading apoptosis. It is …

Background: Pyroptosis is a form of cell death triggered by proinflammatory signals. Recent
studies have reported that oxidized phospholipids function as caspase-11 agonists to …

Pyroptosis is a form of regulated cell death that is characterized by gasdermin processing
and increased membrane permeability. Caspase-1 and caspase-11 have been considered …

Cancer is a category of diseases involving abnormal cell growth with the potential to invade
other parts of the body. Chemotherapy is the most widely used first-line treatment for multiple …

We recently found that Sodium butyrate (NaB) possesses anti-inflammatory effects in
diabetic nephropathy (DN) mouse model and in high-glucose induced mouse glomerular …

Pyroptosis is a programmed cell death caused by inflammasomes, which can detect cell
cytosolic contamination or disturbance. In pyroptosis, caspase-1 or caspase-11/4/5 is …

Pyroptosis, a form of programmed cell death, has garnered increasing attention as it relates
to innate immunity and diseases. The discovery of caspase-1/3/4/5/8/11 function in sensing …

Pyroptosis is a recently described mechanism of programmed cell death mediated by
proteins of the gasdermin family. Widely recognized signaling cascades include the …