Context: Increased adipose tissue lipolytic activity is considered an important factor in the
pathogenesis of skeletal muscle insulin resistance associated with obesity. Objective: The …

The present study was performed in 17 nondiabetic subjects and was initiated to determine
whether enhanced adipose tissue lipolysis, either basal or catecholamine induced …

This study evaluated the ability of insulin to regulate free fatty acid (FAA) concentrations in
healthy nondiabetic subjects selected to be either insulin-resistant or-sensitive on the basis …

Skeletal muscle insulin resistance (IR) is typically severe in type 2 diabetes mellitus (DM).
However, the factors that account for interindividual differences in the severity of IR are not …

In addition to sc and visceral fat deposits, muscle has been shown to contain relevant
amounts of lipids whose breakdown is subject to hormonal regulation. The aim of the …

Abstract Context and Objective: Adipose tissue insulin resistance may cause hepatic and
skeletal muscle insulin resistance by releasing excess free fatty acids (FFAs). Because no …

Background Although it is well-accepted that increased plasma free fatty acid (FFA)
concentration causes lipid overload and muscle insulin resistance in people with obesity …

Insulin resistance in adipose tissue increases the release of free fatty acids into the
circulation, which likely contributes to impaired insulin action in liver and skeletal muscle …

A close relationship between elevated plasma free fatty acid (FFA) levels and insulin
resistance is commonly reported in obese subjects. The aim of the present study was to …

Disturbances in skeletal muscle lipid metabolism may precede or contribute to the
development of whole body insulin resistance. In this study, we examined fasting and …