Excessive fat turnover and oxidation might cause the insulin resistance of carbohydrate
metabolism in obese humans. We studied the response of free fatty acid (FFA) metabolism …

Context: Animal studies revealed that medium-chain fatty acids (MCFA), due to their
metabolic characteristics, are not stored in skeletal muscle and may therefore not give rise to …

Using stable isotopic labeling of dietary fatty acids in conjunction with arteriovenous
difference measurements, we have assessed the regulation of lipoprotein lipase-derived …

The regulation of lipolysis, free fatty acid appearance into plasma (FFA R (a)), an FFA
reesterification and oxidation were examined in seven healthy humans infused …

This study was designed to determine the role of visceral adipose tissue (VAT) accumulation
in systemic fat metabolism and to compare this in black and white women who differ in their …

The effect of short-(2 h) and long-term (24 h) low-grade Intralipid infusion on whole-body
insulin action, cellular glucose metabolism, and proximal components of the insulin signal …

Insulin stimulates the translocation fatty acid transport protein 1 (FATP1) to plasma
membrane, and thus greater free fatty acid (FFA) uptake, in adipocyte cell models. Whether …

There is a debate on whether lipid-mediated insulin resistance derives from an increased or
decreased capacity of muscle to oxidize fats. Here, we examine the involvement of muscle …

The increase in free fatty acid flux resulting from increased lipolysis secondary to adipose-
tissue insulin resistance induces or aggravates insulin resistance in liver and muscle …

To examine the mechanism by which lipids cause insulin resistance in humans, skeletal
muscle glycogen and glucose-6-phosphate concentrations were measured every 15 min by …