Labeled oxytocin administered via the intranasal route reaches the brain in rhesus macaques
MR Lee, TA Shnitko, SW Blue, AV Kaucher… - Nature …, 2020 - nature.com
Oxytocin may have promise as a treatment for neuropsychiatric disorders. Its therapeutic
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …
effect may depend on its ability to enter the brain and bind to the oxytocin receptor. To date …
Oxytocin by intranasal and intravenous routes reaches the cerebrospinal fluid in rhesus macaques: determination using a novel oxytocin assay
MR Lee, KB Scheidweiler, XX Diao, F Akhlaghi… - Molecular …, 2018 - nature.com
Oxytocin (OT) is a potential treatment for multiple neuropsychiatric disorders. As OT is a
peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies …
peptide, delivery by the intranasal (IN) route is the preferred method in clinical studies …
Evidence for intranasal oxytocin delivery to the brain: recent advances and future perspectives
DS Quintana, KT Smerud, OA Andreassen… - Therapeutic …, 2018 - Taylor & Francis
The neuropeptide oxytocin plays an evolutionarily conserved role in mammalian social
behavior. Despite striking effects on animal social behavior after intracerebroventricular drug …
behavior. Despite striking effects on animal social behavior after intracerebroventricular drug …
Oxytocin delivered nasally or intraperitoneally reaches the brain and plasma of normal and oxytocin knockout mice
Intranasal delivery of oxytocin (Oxt) has been identified as a potential therapeutic to target
human conditions characterized by social deficits, yet the ability of this administrative route …
human conditions characterized by social deficits, yet the ability of this administrative route …
Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research
DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …
behavior have steadily increased over the last two decades, stimulating considerable …
Effects of route of administration on oxytocin-induced changes in regional cerebral blood flow in humans
DA Martins, N Mazibuko, F Zelaya… - Nature …, 2020 - nature.com
Could nose-to-brain pathways mediate the effects of peptides such as oxytocin (OT) on brain
physiology when delivered intranasally? We address this question by contrasting two …
physiology when delivered intranasally? We address this question by contrasting two …
Plasma and CSF oxytocin levels after intranasal and intravenous oxytocin in awake macaques
SM Freeman, S Samineni, PC Allen… - …, 2016 - Elsevier
Oxytocin (OT) is a neuropeptide that mediates a variety of complex social behaviors in
animals and humans. Intranasal OT has been used as an experimental therapeutic for …
animals and humans. Intranasal OT has been used as an experimental therapeutic for …
Oxytocin-augmented psychotherapy: beware of context
R Hurlemann - Neuropsychopharmacology, 2017 - ncbi.nlm.nih.gov
The hypothalamic peptide oxytocin modulates a wide range of social and cognitive functions
in humans and nonhuman primates. As a result, much effort is currently being devoted to …
in humans and nonhuman primates. As a result, much effort is currently being devoted to …
CSF and blood oxytocin concentration changes following intranasal delivery in macaque
O Dal Monte, PL Noble, J Turchi, A Cummins… - PloS one, 2014 - journals.plos.org
Oxytocin (OT) in the central nervous system (CNS) influences social cognition and behavior,
making it a candidate for treating clinical disorders such as schizophrenia and autism …
making it a candidate for treating clinical disorders such as schizophrenia and autism …
Nasal oxytocin for the treatment of psychiatric disorders and pain: achieving meaningful brain concentrations
DC Yeomans, LR Hanson, DS Carson… - Translational …, 2021 - nature.com
There is evidence of the therapeutic potential of intranasal oxytocin for the treatment of pain
and various psychiatric disorders, however, there is scant evidence that oxytocin reaches …
and various psychiatric disorders, however, there is scant evidence that oxytocin reaches …
相关搜索
- labeled oxytocin rhesus macaques
- labeled oxytocin intranasal route
- rhesus macaques cerebrospinal fluid
- brain concentrations nasal oxytocin
- psychiatric disorders nasal oxytocin
- intranasal delivery blood oxytocin
- awake macaques oxytocin levels
- concentration changes blood oxytocin
- cerebrospinal fluid oxytocin assay
- rhesus macaques intranasal route
- rhesus macaques oxytocin assay
- concentration changes intranasal delivery