Characterization and inception of a triterpenoid astrakurkurol, as a cytotoxic molecule on human hepatocellular carcinoma cells, Hep3B

S Nandi, S Chandra, R Sikder… - Journal of agricultural …, 2019 - ACS Publications
Mushrooms are customary influential sources of pharmaceutically active metabolites.
Usually lanostane-type triterpenoids from mushrooms had prospective for cancer disease …

Anti‐cancer effect of astrakurkurol from a folklore tribal mushroom on human hepatocellular carcinoma cells via mediating cell cycle inhibition, apoptosis, and …

S Nandi, A Adhikary, K Acharya - Journal of Food Biochemistry, 2022 - Wiley Online Library
Astraeus hygrometricus extensively been utilized by tribal people for long time. A triterpene,
astrakurkurol has been isolated from A. hygrometricus but anticancer effect of this novel …

Astrakurkurone, a sesquiterpenoid from wild edible mushroom, targets liver cancer cells by modulating bcl‐2 family proteins

A Dasgupta, D Dey, D Ghosh, TK Lai… - IUBMB …, 2019 - Wiley Online Library
Induction of apoptosis is the target of choice for modern chemotherapeutic treatment of
cancer, where lack of potent “target‐specific” drugs has led to extensive research on …

A natural derivative from ethnomedicinal mushroom potentiates apoptosis, autophagy and attenuates cell migration, via fine tuning the Akt signaling in human lung …

S Nandi, P Upadhyay, A Roy… - Environmental …, 2022 - Wiley Online Library
Although comprehensive exertions have been made in late decades for treating advanced
lung cancer with inclusive therapies but efficient anti‐lung cancer therapeutics are statically …

Mushrooms are potential foods against cancer: Identified by molecular docking and molecular dynamics simulation

S Debnath, D Sen - Natural Product Research, 2022 - Taylor & Francis
Abstract Epidermal Growth Factor Receptor (EGFR) is a promising drug target for the
discovery of cancer chemotherapeutics. EGFR tyrosine kinase inhibitors become resistant …

[HTML][HTML] Auranofin enhances sulforaphane-mediated apoptosis in hepatocellular carcinoma Hep3B cells through inactivation of the PI3K/Akt signaling pathway

H Hwangbo, SY Kim, H Lee, SH Park… - Biomolecules & …, 2020 - ncbi.nlm.nih.gov
The thioredoxin (Trx) system plays critical roles in regulating intracellular redox levels and
defending organisms against oxidative stress. Recent studies indicated that Trx reductase …

[HTML][HTML] Taraxerol induces cell apoptosis through a mitochondria-mediated pathway in HeLa cells

X Yao, B Lu, C Lü, Q Bai, D Yan, H Xu - Cell Journal (Yakhteh), 2017 - ncbi.nlm.nih.gov
Objective Taraxerol acetate has potent anti-cancer effects via the induction of apoptosis,
autophagy, cell cycle arrest, and inhibition of cell migration. However, whether taraxerol …

Saururus chinensis Baill induces apoptosis through endoplasmic reticulum stress in HepG2 hepatocellular carcinoma cells

AY Lee, YA Han, JE Kim, SH Hong, EJ Park… - Food and Chemical …, 2015 - Elsevier
In this study, we examined the mechanism underlying the effect of Saururus chinensis Baill
(saururaceae) on hepatocellular carcinoma HepG2 cells. HepG2 cells and Chang cells were …

Cell cycle arrest and apoptosis in human liver cancer cell line and A549 cell lines by Turbiconol–A novel sterol isolated from Turbinaria conoides

KK Jacob, KJP Peter, SM Nair… - Pharmacognosy …, 2019 - phcog.com
Background: Turbinaria conoides, a brown seaweed, is a rich source of oxygenated
fucosterols which are capable of suppressing the proliferation of cancer cells. Their specific …

[HTML][HTML] Libertellenone H, a natural pimarane diterpenoid, inhibits thioredoxin system and induces ROS-mediated apoptosis in human pancreatic cancer cells

W Zhang, Y Zhu, H Yu, X Liu, B Jiao, X Lu - Molecules, 2021 - mdpi.com
Libertellenone H (LH), a marine-derived pimarane diterpenoid isolated from arctic fungus
Eutypella sp. D-1, has shown effective cytotoxicity on a range of cancer cells. The present …