Biological properties of milk-derived extracellular vesicles and their physiological functions in infant

X Jiang, L You, Z Zhang, X Cui, H Zhong… - Frontiers in Cell and …, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by all cells under pathological and physiological
conditions. EVs harbor various biomolecules, including protein, lipid, non-coding RNA …

Milk-derived extracellular vesicles in inter-organism, cross-species communication and drug delivery

R Sanwlani, P Fonseka, SV Chitti, S Mathivanan - Proteomes, 2020 - mdpi.com
Milk is considered as more than a source of nutrition for infants and is a vector involved in
the transfer of bioactive compounds and cells. Milk contains abundant quantities of …

The therapeutic potential of breast milk-derived extracellular vesicles

JD Galley, GE Besner - Nutrients, 2020 - mdpi.com
In the past few decades, interest in the therapeutic benefits of exosomes and extracellular
vesicles (EVs) has grown exponentially. Exosomes/EVs are small particles which are …

Exosome-derived microRNAs of human milk and their effects on infant health and development

BC Melnik, W Stremmel, R Weiskirchen, SM John… - Biomolecules, 2021 - mdpi.com
Multiple biologically active components of human milk support infant growth, health and
development. Milk provides a wide spectrum of mammary epithelial cell-derived …

Abundantly present miRNAs in milk-derived extracellular vesicles are conserved between mammals

MJC Herwijnen, TAP Driedonks, BL Snoek… - Frontiers in …, 2018 - frontiersin.org
Mammalian milk is not only a source of nutrition for the newborn, but also contains various
components that regulate further development. For instance, milk is an abundant source of …

[HTML][HTML] Biological activities of extracellular vesicles and their cargos from bovine and human milk in humans and implications for infants

J Zempleni, A Aguilar-Lozano, M Sadri, S Sukreet… - The Journal of …, 2017 - Elsevier
Extracellular vesicles (EVs) in milk harbor a variety of compounds, including lipids, proteins,
noncoding RNAs, and mRNAs. Among the various classes of EVs, exosomes are of …

Acidification effects on isolation of extracellular vesicles from bovine milk

MM Rahman, K Shimizu, M Yamauchi, H Takase… - PLoS …, 2019 - journals.plos.org
Bovine milk extracellular vesicles (EVs) attract research interest as carriers of biologically
active cargo including miRNA from donor to recipient cells to facilitate intercellular …

Extracellular vesicles in human milk

Y Hu, J Thaler, R Nieuwland - Pharmaceuticals, 2021 - mdpi.com
Milk supports the growth and development of infants. An increasing number of mostly recent
studies have demonstrated that milk contains a hitherto undescribed component called …

Comprehensive proteomic analysis of human milk-derived extracellular vesicles unveils a novel functional proteome distinct from other milk components

MJC van Herwijnen, MI Zonneveld, S Goerdayal… - Molecular & Cellular …, 2016 - ASBMB
Breast milk contains several macromolecular components with distinctive functions, whereby
milk fat globules and casein micelles mainly provide nutrition to the newborn, and whey …

Breast milk-derived extracellular vesicles enriched in exosomes from mothers with type 1 diabetes contain aberrant levels of microRNAs

AH Mirza, S Kaur, LB Nielsen, J Størling… - Frontiers in …, 2019 - frontiersin.org
The breast milk plays a crucial role in shaping the initial intestinal microbiota and mucosal
immunity of the infant. Interestingly, breastfeeding has proven to be protective against the …