Characterization of CSF inflammatory markers after hemorrhagic stroke and their relationship to disease severity

J Magid-Bernstein, J Yan, AL Herman, Z He… - medRxiv, 2023 - medrxiv.org
Background: The inflammatory response within the central nervous system is a key driver of
secondary brain injury after hemorrhagic stroke, both in patients with intracerebral …

Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke

P Welsh, M Barber, P Langhorne, A Rumley… - Cerebrovascular …, 2009 - karger.com
Background: Many inflammatory and haemostatic biomarkers show associations with acute
ischaemic stroke outcome, but few studies compare a large range of markers. Methods: We …

The temporal profile of inflammatory markers and mediators in blood after acute ischemic stroke differs depending on stroke outcome

H Worthmann, AB Tryc, A Goldbecker, YT Ma… - Cerebrovascular …, 2010 - karger.com
Background: Early inflammation has been suggested as an important factor contributing to
unfavorable prognosis after acute ischemic stroke. The present study aimed to clarify the …

Secondary injury and inflammation after intracerebral haemorrhage: a systematic review and meta-analysis of molecular markers in patient brain tissue

JJM Loan, C Kirby, K Emelianova… - Journal of Neurology …, 2022 - jnnp.bmj.com
Background Inflammatory responses to intracerebral haemorrhage (ICH) are potential
therapeutic targets. We aimed to quantify molecular markers of inflammation in human brain …

Selected acute phase CSF factors in ischemic stroke: findings and prognostic value

M Beridze, T Sanikidze, R Shakarishvilil, N Intskirveli… - BMC neurology, 2011 - Springer
Background Study aimed at investigation of pathogenic role and prognostic value of several
selected cerebrospinal fluid acute phase factors that can reflect the severity of ischemic …

Inflammation in delayed ischemia and functional outcomes after subarachnoid hemorrhage

SH Ahn, JPJ Savarraj, K Parsha… - Journal of …, 2019 - Springer
Background Inflammatory mechanism has been implicated in delayed cerebral ischemia
(DCI) and poor functional outcomes after subarachnoid hemorrhage (SAH). Identification of …

Inflammatory biomarkers in blood of patients with acute brain ischemia

S Sotgiu, B Zanda, B Marchetti, ML Fois… - European Journal of …, 2006 - Wiley Online Library
Although many failed surrogate markers are provided in the literature, inflammation may
contribute to the outcome of ischemic stroke. In 50 consecutive patients with acute ischemic …

CCL 2 and CXCL 10 are associated with poor outcome after intracerebral hemorrhage

MJ Landreneau, MT Mullen, SR Messé… - Annals of Clinical …, 2018 - Wiley Online Library
Objective Intracerebral hemorrhage carries a high mortality and survivors are frequently left
with significant disability. Immunological mechanisms may play an important role in …

[HTML][HTML] Cytokine registry in stroke patients (CRISP): Protocol of a prospective observational study

M Farooqui, A Ikram, S Suriya, S Saleem, SA Quadri… - Medicine, 2020 - journals.lww.com
Inflammation is an important pathophysiological process after an acute stroke (AS). Pro-and
anti-inflammatory molecules (cytokines and interleukins) are the key players during this …

Inflammasome caspase-1 activity is elevated in cerebrospinal fluid after aneurysmal subarachnoid hemorrhage and predicts functional outcome

Y Hirsch, JR Geraghty, EA Katz, FD Testai - Neurocritical care, 2021 - Springer
Abstract Background/Objective Subarachnoid hemorrhage (SAH) is a devastating
neurological injury, further complicated by few available methods to objectively predict …