Oligonucleotides containing 4′-carboxy-, 4′-methoxycarbonyl-, 4′-carbamoyl-, and 4′-
methylcarbamoyl-thymidines, and their 2′-methoxy, 2′-amino or 2′-acetamido analogs …

2′, 4′-Bridged nucleic acid (2′, 4′-BNA) analogues are used for therapeutic
oligonucleotides, owing to their excellent hybridizing ability with complementary RNA and …

The N-acetyl derivatives 1a and 2a of the aminotriazole and aminoimidazole 2′-
deoxynucleosides 1 and 2 were synthesized as potential substitutes of protonated 2 …

Oligonucleotides containing 4′-C-aminomethyl-2′-O-methyl or 4′-C-aminomethyl-2′-
deoxy-2′-fluoro modified thymidines have been synthesized. Compared with the …

Oligodeoxynucleotides containing the double-headed nucleoside 5′(S)-C-(2-(thymin-1-yl)
ethyl) thymidine were prepared by standard solid phase synthesis. The synthetic building …

The synthesis of four novel 3′‐C‐branched and 4′‐C‐branched nucleosides and their
transformation into the corresponding 3′‐O‐phosphoramidite building blocks for …

Procedures are described for synthesis via solid support methodology of oligonucleotide
analogues derived in part from 3′-amino-3′-deoxythymidine or 5′-amino-5 …

Bicyclic nucleoside analogues with a fixed N-type conformation, 2′-O, 4′-C-
methyleneuridine and-cytidine, were incorporated into oligonucleotides, and the binding …

Convergent synthesis of β-and α-1-(3-C-allyl-2-deoxy-D-erythro-pentofuranosyl) thymine
and their incorporation into β-and α-oligodeoxynucleotides (ODNs) is described. The …

Artificial thymidine monomers possessing amide or N-methylamide bridges were designed,
synthesized, and introduced into oligonucleotides. UV-melting experiments showed that …