Dissecting the roles of gonadotropin-inhibitory hormone in mammals: studies using pharmacological tools and genetically modified mouse models
S Leon, M Tena-Sempere - Frontiers in Endocrinology, 2016 - frontiersin.org
Reproduction is essential for perpetuation of the species and, hence, is controlled by a
sophisticated network of regulatory factors of central and peripheral origin that integrate at …
sophisticated network of regulatory factors of central and peripheral origin that integrate at …
Kisspeptins and reproduction: physiological roles and regulatory mechanisms
L Pinilla, E Aguilar, C Dieguez, RP Millar… - Physiological …, 2012 - journals.physiology.org
Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …
have evolved to mediate the diverse internal and external environmental inputs that regulate …
Cellular mechanisms and integrative timing of neuroendocrine control of GnRH secretion by kisspeptin
The hypothalamus integrates endogenous and exogenous inputs to control the pituitary–
gonadal axis. The ultimate hypothalamic influence on reproductive activity is mediated …
gonadal axis. The ultimate hypothalamic influence on reproductive activity is mediated …
Exogenous kisspeptin enhances seasonal reproductive function in male Siberian hamsters
AM Bailey, SJ Legan, GE Demas - Functional Ecology, 2017 - Wiley Online Library
Animals living in temperate climates are faced with the challenge of reproducing only when
environmental conditions are suitable for offspring survival. Environmental cues signalling …
environmental conditions are suitable for offspring survival. Environmental cues signalling …
Origin and evolution of the neuroendocrine control of reproduction in vertebrates, with special focus on genome and gene duplications
S Dufour, B Quérat, H Tostivint… - Physiological …, 2020 - journals.physiology.org
In humans, as in the other mammals, the neuroendocrine control of reproduction is ensured
by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are …
by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are …
Kobayashi Award 2019: The neuroendocrine regulation of the mammalian reproduction
H Tsukamura - General and comparative endocrinology, 2022 - Elsevier
Mammalian reproductive function is a complex system of many players orchestrated by the
hypothalamus-pituitary–gonadal (HPG) axis. The hypothalamic gonadotropin-releasing …
hypothalamus-pituitary–gonadal (HPG) axis. The hypothalamic gonadotropin-releasing …
Kisspeptins and the control of gonadotropin secretion in male and female rodents
J Roa, JM Castellano, VM Navarro, DJ Handelsman… - Peptides, 2009 - Elsevier
Kisspeptins, the products of KiSS-1 gene acting via G protein-coupled receptor 54 (GPR54),
have recently emerged as fundamental gatekeepers of gonadal function by virtue of their …
have recently emerged as fundamental gatekeepers of gonadal function by virtue of their …
Response to exogenous kisspeptin varies according to sex and reproductive condition in Siberian hamsters (Phodopus sungorus)
Most animals experience marked changes in reproductive status across development that
are regulated by changes in the hypothalamo–pituitary–gonadal (HPG) axis. The upstream …
are regulated by changes in the hypothalamo–pituitary–gonadal (HPG) axis. The upstream …
Kisspeptin neurons as a key player bridging the endocrine system and sexual behavior in mammals
Reproductive behaviors are sexually differentiated: for example, male rodents show
mounting behavior, while females in estrus show lordosis behavior as sex-specific sexual …
mounting behavior, while females in estrus show lordosis behavior as sex-specific sexual …
Kisspeptin: past, present, and prologue
RA Steiner - Kisspeptin Signaling in Reproductive Biology, 2013 - Springer
Research in the nineteenth and early twentieth century established that the brain awakens
reproduction, governs reproductive activity in the adult of virtually all vertebrates. By 1950 …
reproduction, governs reproductive activity in the adult of virtually all vertebrates. By 1950 …