Reproduction is essential for perpetuation of the species and, hence, is controlled by a
sophisticated network of regulatory factors of central and peripheral origin that integrate at …

Procreation is essential for survival of species. Not surprisingly, complex neuronal networks
have evolved to mediate the diverse internal and external environmental inputs that regulate …

The hypothalamus integrates endogenous and exogenous inputs to control the pituitary–
gonadal axis. The ultimate hypothalamic influence on reproductive activity is mediated …

Animals living in temperate climates are faced with the challenge of reproducing only when
environmental conditions are suitable for offspring survival. Environmental cues signalling …

In humans, as in the other mammals, the neuroendocrine control of reproduction is ensured
by the brain-pituitary gonadotropic axis. Multiple internal and environmental cues are …

Mammalian reproductive function is a complex system of many players orchestrated by the
hypothalamus-pituitary–gonadal (HPG) axis. The hypothalamic gonadotropin-releasing …

Kisspeptins, the products of KiSS-1 gene acting via G protein-coupled receptor 54 (GPR54),
have recently emerged as fundamental gatekeepers of gonadal function by virtue of their …

Most animals experience marked changes in reproductive status across development that
are regulated by changes in the hypothalamo–pituitary–gonadal (HPG) axis. The upstream …

Reproductive behaviors are sexually differentiated: for example, male rodents show
mounting behavior, while females in estrus show lordosis behavior as sex-specific sexual …

Research in the nineteenth and early twentieth century established that the brain awakens
reproduction, governs reproductive activity in the adult of virtually all vertebrates. By 1950 …