[HTML][HTML] Ocular drug delivery barriers—role of nanocarriers in the treatment of anterior segment ocular diseases
Ocular drug delivery is challenging due to the presence of anatomical and physiological
barriers. These barriers can affect drug entry into the eye following multiple routes of …
barriers. These barriers can affect drug entry into the eye following multiple routes of …
Drug delivery to the eye: what benefits do nanocarriers offer?
RR Joseph, SS Venkatraman - Nanomedicine, 2017 - Taylor & Francis
Ocular drug delivery has seen several advances in the past few decades, with respect to
new drugs, improved formulations, targeted delivery, as well as exploration of new routes of …
new drugs, improved formulations, targeted delivery, as well as exploration of new routes of …
A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: Challenges analysis and recent advances
R Wang, Y Gao, A Liu, G Zhai - Journal of drug targeting, 2021 - Taylor & Francis
Posterior segment eye disease is a leading cause of irreversible vision impairment and
blindness. As the unique organ for vision, eyes are protected by various protective barriers …
blindness. As the unique organ for vision, eyes are protected by various protective barriers …
[HTML][HTML] Nanocarriers for ocular drug delivery: Current status and translational opportunity
S Gorantla, VK Rapalli, T Waghule, PP Singh… - RSC …, 2020 - pubs.rsc.org
Ocular diseases have a significant effect on vision and quality of life. Drug delivery to ocular
tissues is a challenge to formulation scientists. The major barriers to delivering drugs to the …
tissues is a challenge to formulation scientists. The major barriers to delivering drugs to the …
Target strategies for drug delivery bypassing ocular barriers
The eye is a directly accessible sensitive organ, impairment of which causes direct effect on
the quality of life. Efficient ocular drug delivery remains a major challenge for the …
the quality of life. Efficient ocular drug delivery remains a major challenge for the …
Novel strategies for anterior segment ocular drug delivery
K Cholkar, SP Patel, AD Vadlapudi… - Journal of ocular …, 2013 - liebertpub.com
Research advancements in pharmaceutical sciences have led to the development of new
strategies in drug delivery to anterior segment. Designing a new delivery system that can …
strategies in drug delivery to anterior segment. Designing a new delivery system that can …
Ocular drug delivery: present innovations and future challenges
Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …
Ocular novel drug delivery: impacts of membranes and barriers
Background: Ocular drug delivery is an extremely challenging area due to its restrictive
barrier functionalities. Objective: Drug transport via corneal/non-corneal routes involves …
barrier functionalities. Objective: Drug transport via corneal/non-corneal routes involves …
Recent advance of nanoparticle-based topical drug delivery to the posterior segment of the eye
Y Wang, X Xu, Y Gu, Y Cheng, F Cao - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Considering that the number of patients afflicted by posterior eye diseases is
increasing, effective drug delivery is currently in high clinical demand. Topical administration …
increasing, effective drug delivery is currently in high clinical demand. Topical administration …
Nanotherapies for the treatment of ocular diseases
S Reimondez-Troitiño, N Csaba, MJ Alonso… - European Journal of …, 2015 - Elsevier
The topical route is the most frequent and preferred way to deliver drugs to the eye.
Unfortunately, the very low ocular drug bioavailability (less than 5%) associated with this …
Unfortunately, the very low ocular drug bioavailability (less than 5%) associated with this …