Terminally differentiated neutrophils are short-lived but the key effector cells of the innate
immune response, and have a prominent role in the pathogenesis and propagation of many …

Neutrophils are the most abundant leukocyte and play a central role in the immune defense
against rapidly dividing bacteria. However, they are also the shortest lived cell in the blood …

Successful resolution of inflammation requires inflammatory cells such as neutrophils to
undergo apoptosis prior to non‐inflammatory phagocytosis by professional phagocytes …

Apoptosis is essential for clearance of potentially injurious inflammatory cells and
subsequent efficient resolution of inflammation. Here we report that human neutrophils …

Neutrophils play a central role in host defense and are recruited in vast numbers to sites of
infection where they phagocytose and kill invading bacterial pathogens. Neutrophils have a …

Neutrophils not only play a critical role as a first line of defense against bacteria and fungi
infections but also contribute to tissue injury associated with autoimmune and inflammatory …

Apoptosis of granulocytes and the subsequent clearance of apoptotic cells are important
processes for the successful resolution of inflammation. Signalling pathways, including …

Neutrophils are essential for host defense and their programmed cell death and removal are
critical for the optimal expression as well as for efficient resolution of inflammation. Delayed …

Neutrophilic inflammation is tightly regulated and subsequently resolves to limit tissue
damage and promote repair. When the timely resolution of inflammation is dysregulated …

The cyclin‐dependent kinase inhibitor (CDKi) drugs such as R‐roscovitine have emerged as
potential anti‐inflammatory, pharmacological agents that can influence the resolution of …