Using skeletal muscle homogenates for respirometry has many advantages, but the main
challenge is avoiding the damage to outer mitochondrial membrane (OMM) and complex I …

Most of the knowledge about cell respiration is based on studies of isolated enzymes and
mitochondria. Although essential to identify the biochemical mechanisms and sites of …

The use of near-infrared spectroscopy to measure noninvasively changes in the redox state
of cerebral cytochrome oxidase in vivo is controversial. We therefore tested these …

High resolution respirometry in combination with the skinned fiber technique offers the
possibility to study mitochondrial function routinely in small amounts of human muscle …

Patients with chronic heart failure (HF) have a reduced skeletal muscle blood flow which can
in part explain reduced exercise tolerance and increased ventilation. All the techniques …

Evaluation of Muscle Oxygenation during Exercise by NIRS in Normal Subjects—Significance
of the NIRS Threshold— Page 1 21 THE JOURNAL of JAPANESE COLLEGE of ANGIOLOGY …

A 27-yr-old woman with lifelong severe exercise intolerance manifested by muscle fatigue,
lactic acidosis, and prominent symptoms of dyspnea and tachycardia induced by trivial …

The inability of the brain to withstand more than a brief period of hypoxia is often the limiting
factor determining survival for a variety of clinical conditions, most notably the adult …

Patients with chronic heart failure (CHF) are frequently limited by muscle fatigue resulting
from impaired skeletal muscle blood flow. Accordingly, we assessed working skeletal …

Background—Near infrared spectroscopy can be used in non-invasive monitoring of
changes in skeletal muscle oxygenation in exercising subjects. Objective—To evaluate …