Characteristics of Extracellular Vesicles Released by the Pathogenic Yeast-Like Fungi Candida glabrata, Candida parapsilosis and Candida tropicalis

J Karkowska-Kuleta, K Kulig, E Karnas, E Zuba-Surma… - Cells, 2020 - mdpi.com
Candida spp. yeast-like fungi are opportunistic pathogens in humans and have been
recently found to release extracellular vesicles (EVs) that are involved in many vital …

Candida albicans hyphal extracellular vesicles are different from yeast ones, carrying an active proteasome complex and showing a different role in host immune …

R Martínez-López, ML Hernáez, E Redondo… - Microbiology …, 2022 - Am Soc Microbiol
Candida albicans is the principal causative agent of lethal fungal infections, predominantly
in immunocompromised hosts. Extracellular vesicles (EVs) have been described as crucial …

Proteomics Unravels Extracellular Vesicles as Carriers of Classical Cytoplasmic Proteins in Candida albicans

A Gil-Bona, A Llama-Palacios, CM Parra… - Journal of proteome …, 2015 - ACS Publications
The commensal fungus Candida albicans secretes a considerable number of proteins and,
as in different fungal pathogens, extracellular vesicles (EVs) have also been observed. Our …

Fungal extracellular vesicles with a focus on proteomic analysis

MR Bleackley, CS Dawson, MA Anderson - Proteomics, 2019 - Wiley Online Library
Extracellular vesicles (EVs) perform crucial functions in cell–cell communication. The
packaging of biomolecules into membrane‐enveloped vesicles prior to release into the …

Insight Into the Properties and Immunoregulatory Effect of Extracellular Vesicles Produced by Candida glabrata, Candida parapsilosis, and Candida tropicalis …

K Kulig, E Karnas, O Woznicka, P Kuleta… - Frontiers in cellular …, 2022 - frontiersin.org
Currently, non-albicans Candida species, including C. tropicalis, C. glabrata, and C.
parapsilosis, are becoming an increasing epidemiological threat, predominantly due to the …

A comparative analysis of protein virulence factors released via extracellular vesicles in two Candida albicans strains cultivated in a nutrient-limited medium

K Konečná, J Klimentová, O Benada, I Němečková… - Microbial …, 2019 - Elsevier
One of the pathways for the delivery of virulence effector molecules into the extracellular
environment of Candida albicans relies on the release of membrane-bound carriers which …

Extracellular vesicle-associated transitory cell wall components and their impact on the interaction of fungi with host cells

L Nimrichter, MM De Souza, M Del Poeta… - Frontiers in …, 2016 - frontiersin.org
Classic cell wall components of fungi comprise the polysaccharides glucans and chitin, in
association with glycoproteins and pigments. During the last decade, however, system …

Extracellular Vesicles from Candida haemulonii var. vulnera Modulate Macrophage Oxidative Burst

BTM Oliveira, TMH Dourado, PWS Santos… - Journal of Fungi, 2023 - mdpi.com
Members of the Candida haemulonii species complex are multidrug-resistant emergent
yeast pathogens able to cause superficial and invasive infections in risk populations. Fungal …

Protein markers for Candida albicans EVs include claudin-like Sur7 family proteins

CS Dawson, D Garcia-Ceron… - Journal of …, 2020 - Taylor & Francis
ABSTRACT Background: Fungal extracellular vesicles (EVs) have been implicated in host-
pathogen and pathogen-pathogen communication in some fungal diseases. In depth …

The impact of proteomics on the understanding of functions and biogenesis of fungal extracellular vesicles

ML Rodrigues, ES Nakayasu, IC Almeida… - Journal of …, 2014 - Elsevier
Several microbial molecules are released to the extracellular space in vesicle-like
structures. In pathogenic fungi, these molecules include pigments, polysaccharides, lipids …