[PDF][PDF] Cell-based drug delivery devices using phagocytosis-resistant backpacks
MF Rubner, S Mitragotri - Adv Mater, 2011 - academia.edu
Macrophages, ubiquitous phagocytic cells in the human immune system, play a key role in
homeostatic, immunological, and inflammatory processes.[1–2] Macrophages are widely …
homeostatic, immunological, and inflammatory processes.[1–2] Macrophages are widely …
Delivery strategies to control inflammatory response: Modulating M1–M2 polarization in tissue engineering applications
Macrophages are key players in many physiological scenarios including tissue
homeostasis. In response to injury, typically the balance between macrophage sub …
homeostasis. In response to injury, typically the balance between macrophage sub …
Neutrophils and macrophages as targets for development of nanotherapeutics in inflammatory diseases
Neutrophils and macrophages are major components of innate systems, playing central
roles in inflammation responses to infections and tissue injury. If they are out of control …
roles in inflammation responses to infections and tissue injury. If they are out of control …
Living leukocyte‐based drug delivery systems
Leukocytes play a vital role in immune responses, including defending against invasive
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …
pathogens, reconstructing impaired tissue, and maintaining immune homeostasis. When the …
Sequential drug delivery to modulate macrophage behavior and enhance implant integration
EM O'Brien, GE Risser, KL Spiller - Advanced drug delivery reviews, 2019 - Elsevier
Macrophages are major upstream regulators of the inflammatory response to implanted
biomaterials. Sequential functions of distinct macrophage phenotypes are essential to the …
biomaterials. Sequential functions of distinct macrophage phenotypes are essential to the …
Chemical Modulation of in Vivo Macrophage Function with Subpopulation-Specific Fluorescent Prodrug Conjugates
A Fernandez, M Vermeren, D Humphries… - ACS Central …, 2017 - ACS Publications
Immunomodulatory agents represent one of the most promising strategies for enhancing
tissue regeneration without the side effects of traditional drug-based therapies. Tissue repair …
tissue regeneration without the side effects of traditional drug-based therapies. Tissue repair …
Nanoparticle‐laden macrophages for tumor‐tropic drug delivery
Macrophages hold great potential in cancer drug delivery because they can sense
chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …
chemotactic cues and home to tumors with high efficiency. However, it remains a challenge …
Nanoparticles targeting macrophages as potential clinical therapeutic agents against cancer and inflammation
G Hu, M Guo, J Xu, F Wu, J Fan, Q Huang… - Frontiers in …, 2019 - frontiersin.org
With the development of nanotechnology, significant progress has been made in the design,
and manufacture of nanoparticles (NPs) for use in clinical treatments. Recent increases in …
and manufacture of nanoparticles (NPs) for use in clinical treatments. Recent increases in …
Macrophages as tools and targets in cancer therapy
A Mantovani, P Allavena, F Marchesi… - Nature Reviews Drug …, 2022 - nature.com
Tumour-associated macrophages are an essential component of the tumour
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …
Mechanobiology of macrophages: how physical factors coregulate macrophage plasticity and phagocytosis
N Jain, J Moeller, V Vogel - Annual review of biomedical …, 2019 - annualreviews.org
In addition to their early-recognized functions in host defense and the clearance of apoptotic
cell debris, macrophages play vital roles in tissue development, homeostasis, and repair. If …
cell debris, macrophages play vital roles in tissue development, homeostasis, and repair. If …