Progesterone acts via two specific receptors to affect gene transcription in target tissues.
Progesterone receptor (PR) B contains 933 amino acids while PR A is a truncated version …

Materials and Methods Description of Probes. The probe used for screening the cDNA
library, hPR54, was a gift from Dr. BW O'Malley and contained a 2.6-kb fragment of the …

Activated steroid receptors induce chromatin remodeling events in the promoters of some
target genes. We previously reported that transiently expressed progesterone receptor (PR) …

Recently, we have cloned the novel isoform of the progesterone receptor (PR) cDNA (PR
isoform S cDNA) from the human testicular cDNA library. The isoform S cDNA consists of the …

A short conserved α-helix in the carboxyl-terminal activation function of the ligand-binding
domain of steroid hormone receptors, called AF2, is important for ligand-dependent …

In humans, the biological response to progesterone is mediated by two distinct forms of the
progesterone receptor (human (h) PR-A, 94 kDa and hPR-B, 114 kDa). These two isoforms …

Previously we reported the identification of two unique progesterone receptor (PR)
messenger RNA transcripts that encode a smaller PR isoform, termed the C-receptor (PRc) …

The biological response to progesterone is mediated by two distinct forms of the human
progesterone receptor (hPR-A and hPR-B). In most cell contexts, hPR-B functions as a …

Human progesterone receptor (PR) in T47D breast cancer cells is phosphorylated on nine
different serine residues; three are hormone-inducible (Ser 102, Ser 294, and Ser 345) …

The steroid hormone, progesterone, is a central coordinator of all aspects of female
reproductive activity. The physiological effects of progesterone are mediated by interaction …