Abstract Phospholipase A 2 receptor 1 (PLA2R) is a target autoantigen in 70% of patients
with idiopathic membranous nephropathy. We describe the location of a major epitope in the …

Membranous nephropathy (MN) is a common cause of nephrotic syndrome in adults. Recent
clinical studies established that> 70% of patients with idiopathic (also called primary) MN …

The phospholipase A2 receptor (PLA2R1) is the major autoantigen in idiopathic
membranous nephropathy. However, the value of anti-PLA2R1 antibody titers in predicting …

Background Antibodies against phospholipase A 2 receptor 1 (PLA 2 R1) are found in 80%
of patients with membranous nephropathy, and previous studies described three …

Background Idiopathic membranous nephropathy, a common form of the nephrotic
syndrome, is an antibody-mediated autoimmune glomerular disease. Serologic diagnosis …

The M-type phospholipase A2 receptor (PLA 2 R) is the major target antigen in idiopathic
membranous nephropathy with detectable autoantibodies in the serum of up to 70% of …

Results 77.8% of iMN patients in our cohort had antibodies reactive with human PLA 2 R.
The antibody levels in these patients correlated strongly with both clinical status and …

BACKGROUND: Autoantibodies against the M-type phospholipase A2 receptor (PLA2R1)
are specific markers for primary membranous nephropathy (pMN) and anti-PLA2R1 serum …

The phospholipase A2 receptor (PLA2R1) is the major autoantigen in primary membranous
nephropathy. Several PLA2R1 epitopes have been characterized, and a retrospective study …

Autoantibody formation directed against phospholipase A2 receptor (PLA2R) 1 is the
underlying etiology in most cases of primary membranous glomerulopathy. This new …